Evidence map›Paper›PMID 31853871›Full record

ReviewMycopathologia2020

Fatal Disseminated Infection by Trichosporon asahii Under Voriconazole Therapy in a Patient with Acute Myeloid Leukemia: A Review of Breakthrough Infections by Trichosporon spp.

I Ramírez, D Moncada

Abstract readCase ReportsReview
PubMed Publisher
In one paragraph

Review in Mycopathologia, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 34 citations in OpenAlex.

  1. Review
  2. Journal of fungi (Basel, Switzerland) · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Rare Yeasts in Latin America: Uncommon Yet Meaningful.Journal of fungi (Basel, Switzerland) · 2023
    Review
  11. Article
  12. Case Report:Frontiers in pediatrics · 2022
    Article
  13. Article
  14. Urinary Tract Infections Caused by Fluconazole-ResistantOpen forum infectious diseases · 2020
    Article
  15. Review
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

I RamírezInfectious Diseases, Internal Medicine, Hospital Pablo Tobón Uribe, Universidad de Antioquia, calle 78B#69-240, Cra. 51d#62-29, Medellín, Colombia. iramirez@hptu.org.co.ORCID http://orcid.org/0000-0003-4698-1871
D MoncadaInfectious Diseases, Internal Medicine, Hospital Universitario San Vicente Fundación Universidad de Antioquia, Cra. 51d#62-29, Medellín, Colombia.
Hospital Universitario de San Vicente Fundación · COUniversidad de Antioquia · CO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionCases of invasive Trichosporon infections have increasingly emerged; it is now the second leading cause of yeast bloodstream infections after Candida spp., particularly in the immunosuppressed population, where it often causes breakthrough fungemia with high mortality.

methodsWe present a case report of a breakthrough Trichosporon asahii infection in a patient with acute myeloid leukemia and review all of the cases of breakthrough Trichosporon spp. infections published in the literature to date.

resultsWe extracted 68 cases of breakthrough Trichosporon spp. infections, wherein 95.5% patients had hematological malignancy, 61.8% of them occurred in the presence of echinocandins, 22% of triazoles, 13.2% of amphotericin and 3% of other combinations of antifungals. The most prevalent manifestation was fungemia (94%); 82.8% of these were associated with the presence of a central venous catheter. The overall mortality was 68.7%; the patients who survived recovered from the neutropenic event.

conclusionsInvasive trichosporonosis is an acute fatal condition that occurs in immunosuppressed patients, usually under antifungal selective pressure. Typically, neutropenia and its underlying diseases are associated with adverse outcomes.

Indexed as

TrichosporonosisAdultAmphotericin BAntifungal AgentsCentral Venous CathetersEchinocandinsFungemiaHematologic NeoplasmsHumansImmunocompromised HostLeukemia, Myeloid, AcuteMaleMiddle AgedMortalityNeutropeniaTriazolesAmphotericin BAntifungal AgentsEchinocandinsTriazolesVoriconazoleAntifungalBreakthroughFungemiaTrichosporon asahiiTrichosporonosisYeast

Identifiers

PMID31853871
OpenAlexW2994832074

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.