ArticleJournal of clinical monitoring and computing2020
Do changes in perfusion index reflect changes in stroke volume during preload-modifying manoeuvres?
Article in Journal of clinical monitoring and computing, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it.
- ESICM guidelines on circulatory shock and hemodynamic monitoring 2025.Intensive care medicine · 2025Guideline
- Proof of concept of noninvasive detection of norepinephrine induced stroke volume changes using perfusion index in cardiac surgery.Scientific reports · 2026Observational
- The reliability of the plethysmographic perfusion index for detecting fluid responsiveness in critically ill patients.Journal of intensive medicine · 2026Article
- Variation of perfusion index to evaluate fluid responsiveness during the preload challenge tests: a systematic review and meta-analysis.Annals of intensive care · 2026Article
- Feasibility study of using perfusion index to predict the timing of laryngeal mask insertion: an observational study.BMC anesthesiology · 2025Observational
- The Accuracy of the Passive Leg Raising Test Using the Perfusion Index to Identify Preload Responsiveness-A Single Center Study in a Resource-Limited Setting.Diagnostics (Basel, Switzerland) · 2025Article
- Testing preload responsiveness by the tidal volume challenge assessed by the photoplethysmographic perfusion index.Critical care (London, England) · 2024Article
- Peripheral perfusion index of pulse oximetry in adult patients: a narrative review.European journal of medical research · 2024Review
- "The peripheral perfusion index discriminates haemodynamic responses to induction of general anaesthesia".Journal of clinical monitoring and computing · 2023Article
- Association of the perfusion index with postoperative acute kidney injury: a retrospective study.Korean journal of anesthesiology · 2023Article
- How I personalize fluid therapy in septic shock?Critical care (London, England) · 2023Review
- Prediction of fluid responsiveness. What's new?Annals of intensive care · 2022Review
- What is new in hemodynamic monitoring and management?Journal of clinical monitoring and computing · 2022Review
- Prediction of Fluid Responsiveness by the Effect of the Lung Recruitment Maneuver on the Perfusion Index in Mechanically Ventilated Patients During Surgery.Frontiers in medicine · 2022Article
- Perioperative hemodynamic optimization: from guidelines to implementation-an experts' opinion paper.Annals of intensive care · 2021Review
- The ability of pulse oximetry-derived peripheral perfusion index to detect fluid responsiveness in patients with septic shock.Journal of anesthesia · 2021Article
- COVID-19: Pulse oximeters in the spotlight.Journal of clinical monitoring and computing · 2021Article
- Plethysmographic Peripheral Perfusion Index: Could It Be a New Vital Sign?Frontiers in medicine · 2021Review
- Evaluation of fluid responsiveness during COVID-19 pandemic: what are the remaining choices?Journal of anesthesia · 2020Review
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Changes in stroke volume (deltaSV) induced by a lung recruitment manoeuvre (LRM) have been shown to accurately predict fluid responsiveness during protective mechanical ventilation. Cardiac output monitors are used in a limited number of surgical patients. In contrast, all patients are monitored with a pulse oximeter, that may enable the continuous monitoring of a peripheral perfusion index (PI). We postulated that changes in PI (deltaPI) may reflect deltaSV during brief modifications of cardiac preload. We studied 47 patients undergoing neurosurgery and ventilated with a tidal volume of 6-8 ml/kg. All patients were monitored with a pulse contour system enabling the continuous monitoring of SV and with a pulse oximeter enabling the continuous monitoring of PI. LRMs were performed by increasing airway pressure up to 30 cmH
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.