Evidence map›Paper›PMID 31853569›Full record

ArticlePediatric radiology2020

Pediatric chest computed tomography at 100 kVp with tin filtration: comparison of image quality with 70-kVp imaging at comparable radiation dose.

Sophie Vivier, Valérie Deken, Younes Arous, Jean-Baptiste Faivre, Alain Duhamel, Antoine Deschildre, Thomas Flohr, Jacques Remy, Martine Remy-Jardin

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in Pediatric radiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Sophie VivierDepartment of Thoracic Imaging, Hospital Calmette, Blvd Jules Leclercq, 59037, Lille cedex, France.
Valérie DekenSanté Publique: épidémiologie et qualité des soins, University of Lille, CHU Lille, Lille, France.
Younes ArousDepartment of Thoracic Imaging, Hospital Calmette, Blvd Jules Leclercq, 59037, Lille cedex, France.
Jean-Baptiste FaivreDepartment of Thoracic Imaging, Hospital Calmette, Blvd Jules Leclercq, 59037, Lille cedex, France.
Alain DuhamelSanté Publique: épidémiologie et qualité des soins, University of Lille, CHU Lille, Lille, France.
Antoine DeschildrePediatric Pulmonology and Allergy Unit, University of Lille, CHU Lille, Lille, France.
Thomas FlohrDepartment of CT Research & Development, Siemens Healthcare GmbH, Forchheim, Germany.
Jacques RemyDepartment of Thoracic Imaging, Hospital Calmette, Blvd Jules Leclercq, 59037, Lille cedex, France.
Martine Remy-JardinDepartment of Thoracic Imaging, Hospital Calmette, Blvd Jules Leclercq, 59037, Lille cedex, France. martine.remy@chru-lille.fr.
Hôpital Albert Calmette · FRCentre Hospitalier Universitaire de Lille · FRSiemens Healthcare (Germany) · DEUniversité de Lille · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRadiation dose reduction is a primary objective in pediatric populations owing to the well-known risks of radiation-induced cancers. Low-energy photons participate in the radiation dose without significantly contributing to image formation. Their suppression by means of tin filtration should decrease the image noise, anticipating a subsequent application to dose saving.

objectiveTo investigate the level of noise reduction achievable with tin (Sn) filtration at 100 kVp for chest computed tomography (CT) in comparison with a standard scanning mode at 70 kVp with comparable radiation dose. MATERIALS AND

methodsFifty consecutive children (Group 1) underwent non-contrast chest CT examinations on a third-generation dual-source CT system at tin-filtered 100 kVp and pitch 2. The tube-current time product (mAs) was adjusted to maintain the predicted dose length product (DLP) value at 70 kVp for the respective patient. Each child was then paired by weight and age to a child scanned at 70 kVp on the same CT unit (Group 2); Group 2 patients were consecutive patients, retrospectively selected from our database of children prospectively scanned at 70 kVp. Objective and subjective image quality were compared between the two groups of patients to investigate the overall image quality and level of noise reduction that could be subsequently achievable with tin filtration in clinical practice.

resultsThe mean image noise was significantly lower in Group 1 compared to Group 2 when measured in the air (P<0.0001) and inside the aorta (P<0.001). The mean noise reduction was 21.6% (standard deviation [SD] 16.1) around the thorax and 12.0% (SD 32.7) inside the thorax. There was no significant difference in subjective image quality of lung and mediastinal images with excellent overall subjective scores in both groups.

conclusionAt comparable radiation dose, the image noise was found to be reduced by 21.6% compared to the 70-kVp protocol, providing basis for dose reduction without altering image quality in further investigations.

Indexed as

Radiation DosageAdolescentChildChild, PreschoolFemaleHumansInfantMaleProspective StudiesRadiography, ThoracicTinTomography, X-Ray ComputedTinChestChildrenComputed tomographyRadiation doseSpectral shapingTin filtration

Identifiers

PMID31853569
OpenAlexW2995476601

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.