Evidence map›Paper›PMID 31853445›Full record

ArticleBiotechnology reports (Amsterdam, Netherlands)2020

The current strategies and parameters for the enhanced microbial production of 2,3-butanediol.

Olivier Hakizimana, Emmanuel Matabaro, Byong H Lee

Abstract read
In one paragraph

Article in Biotechnology reports (Amsterdam, Netherlands), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Metabolic engineering ofApplied and environmental microbiology · 2024
    Article
  5. Article
  6. The potential of native and engineered Clostridia for biomass biorefining.Frontiers in bioengineering and biotechnology · 2024
    Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Review
  13. Article
  14. Production of Different Biochemicals byFrontiers in microbiology · 2022
    Article
  15. Article
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Olivier HakizimanaSchool of Biotechnology, Jiangnan University, Wuxi, 214122, Jiangsu Prov, China.
Emmanuel MatabaroDepartment of Biology, Institute of Microbiology, ETH Zürich, 8093 Zürich, Switzerland.
Byong H LeeDepartment of Microbiology and Immunology, McGill University, Montreal, QC, H3A2B4, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

2,3-Butanediol (2,3-BD) is a propitious compound with many industrial uses ranging from rubber, fuels, and cosmetics to food additives. Its microbial production has especially attracted as an alternative way to the petroleum-based production. However, 2,3-BD production has always been hampered by low yields and high production costs. The enhanced production of 2,3-butanediol requires screening of the best strains and a systematic optimization of fermentation conditions. Moreover, the metabolic pathway engineering is essential to achieve the best results and minimize the production costs by rendering the strains to use efficiently low cost substrates. This review is to provide up-to-date information on the current strategies and parameters for the enhanced microbial production of 2,3-BD.

Indexed as

2,3-BD, 2,3-Butanediol2, 3-ButanediolackA, acetate kinase-phosphotransacetylaseadhE, alcohol dehydrogenaseAlsD, α-acetolactate decarboxylaseAlsS, α-acetolactate synthaseButanediol dehydrogenasegldA, glycerophosphate dehydrogenase geneKlebsiellaldhA, lactate dehydrogenaseMEK, methyl ethyl ketoneMetabolic engineeringPUMAs, polyurethane-melamidesSpecies

Identifiers

PMID31853445
PMCPMC6911977

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.