Evidence map›Paper›PMID 31853413›Full record

ArticleBiomedical optics express2019

Automated plaque characterization using deep learning on coronary intravascular optical coherence tomographic images.

Juhwan Lee, David Prabhu, Chaitanya Kolluru, Yazan Gharaibeh, Vladislav N Zimin, Hiram G Bezerra, David L Wilson

Abstract read
In one paragraph

Article in Biomedical optics express, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  9. Histology-Grounded Automated Plaque Subtype Segmentation in Intravascular Optical Coherence Tomography.Journal of the Society for Cardiovascular Angiography & Interventions · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Juhwan LeeDepartment of Biomedical Engineering, Case Western Reserve University, Cleveland, OH 44106, USA.
David PrabhuDepartment of Biomedical Engineering, Case Western Reserve University, Cleveland, OH 44106, USA.
Chaitanya KolluruDepartment of Biomedical Engineering, Case Western Reserve University, Cleveland, OH 44106, USA.
Yazan GharaibehDepartment of Biomedical Engineering, Case Western Reserve University, Cleveland, OH 44106, USA.ORCID https://orcid.org/0000-0002-8718-9664
Vladislav N ZiminCardiovascular Imaging Core Laboratory, Harrington Heart & Vascular Institute, University Hospitals Cleveland Medical Center, Cleveland, OH 44106, USA.
Hiram G BezerraCardiovascular Imaging Core Laboratory, Harrington Heart & Vascular Institute, University Hospitals Cleveland Medical Center, Cleveland, OH 44106, USA.
David L WilsonDepartment of Biomedical Engineering, Case Western Reserve University, Cleveland, OH 44106, USA.

Funding

Computer assisted coronary artery stent interventionsR01HL143484 · NHLBI · CASE WESTERN RESERVE UNIVERSITY · PI BEZERRA, HIRAM, WILSON, DAVID LYNN · 2018 to 2021
$2.9M
NHLBI NIH HHS R01 HL143484
6 · The paper itself

Abstract

Accurate identification of coronary plaque is very important for cardiologists when treating patients with advanced atherosclerosis. We developed fully-automated semantic segmentation of plaque in intravascular OCT images. We trained/tested a deep learning model on a folded, large, manually annotated clinical dataset. The sensitivities/specificities were 87.4%/89.5% and 85.1%/94.2% for pixel-wise classification of lipidous and calcified plaque, respectively. Automated clinical lesion metrics, potentially useful for treatment planning and research, compared favorably (<4%) with those derived from ground-truth labels. When we converted the results to A-line classification, they were significantly better (p < 0.05) than those obtained previously by using deep learning classifications of A-lines.

Identifiers

PMID31853413
PMCPMC6913416

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.