Evidence map›Paper›PMID 31853399›Full record

ArticleBiomedical optics express2019

In-vivo 3D corneal elasticity using air-coupled ultrasound optical coherence elastography.

Zi Jin, Reza Khazaeinezhad, Jiang Zhu, Junxiao Yu, Yueqiao Qu, Youmin He, Yan Li, Tomas E Gomez Alvarez-Arenas, Fan Lu, Zhongping Chen

Open access · goldAbstract read
In one paragraph

Article in Biomedical optics express, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 42 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Biomedical optics express · 2024
    Article
  5. Quantitative Optical Coherence Elastography of the Optic Nerve Head In Vivo.IEEE transactions on bio-medical engineering · 2024
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Computational and structural biotechnology journal · 2023
    Review
  15. High-Frequency Ultrasound Elastography to Assess the Nonlinear Elastic Properties of the Cornea and Ciliary Body.IEEE transactions on ultrasonics, ferroelectrics, and frequency control · 2022
    Article
  16. Biomedical optics express · 2022
    Article
  17. Article
  18. Wave-based optical coherence elastography: The 10-year perspective.Progress in biomedical engineering (Bristol, England) · 2022
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 5 countries.

Zi JinBeckman Laser Institute, Department of Biomedical Engineering, University of California, Irvine, Irvine, California 92612, USA.
Reza KhazaeinezhadBeckman Laser Institute, Department of Biomedical Engineering, University of California, Irvine, Irvine, California 92612, USA.
Jiang ZhuBeckman Laser Institute, Department of Biomedical Engineering, University of California, Irvine, Irvine, California 92612, USA.ORCID https://orcid.org/0000-0002-2601-4967
Junxiao YuBeckman Laser Institute, Department of Biomedical Engineering, University of California, Irvine, Irvine, California 92612, USA.
Yueqiao QuBeckman Laser Institute, Department of Biomedical Engineering, University of California, Irvine, Irvine, California 92612, USA.
Youmin HeBeckman Laser Institute, Department of Biomedical Engineering, University of California, Irvine, Irvine, California 92612, USA.
Yan LiBeckman Laser Institute, Department of Biomedical Engineering, University of California, Irvine, Irvine, California 92612, USA.ORCID https://orcid.org/0000-0002-3468-9235
Tomas E Gomez Alvarez-ArenasInstitute of Physical and Information Technologies, Spanish National Research Council (CSIC), 28006 Madrid, Spain.
Fan LuSchool of Ophthalmology and Optometry, Wenzhou Medical University, Wenzhou 325003, Zhejiang, China.
Zhongping ChenBeckman Laser Institute, Department of Biomedical Engineering, University of California, Irvine, Irvine, California 92612, USA.ORCID https://orcid.org/0000-0002-4584-4560
University of California, Irvine · USConsejo Superior de Investigaciones Científicas · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Corneal elasticity can resist elastic deformations under intraocular pressure to maintain normal corneal shape, which has a great influence on corneal refractive function. Elastography can measure tissue elasticity and provide a powerful tool for clinical diagnosis. Air-coupled ultrasound optical coherence elastography (OCE) has been used in the quantification of ex-vivo corneal elasticity. However, in-vivo imaging of the cornea remains a challenge. The 3D air-coupled ultrasound OCE with an axial motion artifacts correction algorithm was developed to distinguish the in-vivo cornea vibration from the axial eye motion in anesthetized rabbits and visualize the elastic wave propagation clearly. The elastic wave group velocity of in-vivo rabbit cornea was measured to be 5.96 ± 0.55 m/s, which agrees with other studies. The results show the potential of 3D air-coupled ultrasound OCE with an axial motion artifacts correction algorithm for quantitative in-vivo assessment of corneal elasticity.

Identifiers

PMID31853399
PMCPMC6913398
OpenAlexW2986370790

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.