Evidence map›Paper›PMID 31853300›Full record

ArticleExperimental and therapeutic medicine2020

A novel CpG-based signature for survival prediction of lung adenocarcinoma patients.

Rongjiong Zheng, Haiqi Xu, Wenjie Mao, Zhennan Du, Mingming Wang, Meiling Hu, Xiaolong Gu

Abstract read
In one paragraph

Article in Experimental and therapeutic medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. A Review of DUSP26: Structure, Regulation and Relevance in Human Disease.International journal of molecular sciences · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Rongjiong ZhengDepartment of Pulmonology, Ningbo Yinzhou Second Hospital, Ningbo, Zhejiang 315192, P.R. China.
Haiqi XuDepartment of Pulmonology, Ningbo Yinzhou Second Hospital, Ningbo, Zhejiang 315192, P.R. China.
Wenjie MaoDepartment of Pulmonology, Ningbo Yinzhou Second Hospital, Ningbo, Zhejiang 315192, P.R. China.
Zhennan DuDepartment of Pulmonology, Ningbo Yinzhou Second Hospital, Ningbo, Zhejiang 315192, P.R. China.
Mingming WangDepartment of Pulmonology, Ningbo Yinzhou Second Hospital, Ningbo, Zhejiang 315192, P.R. China.
Meiling HuDepartment of Surgery, Cixi People's Hospital of Zhejiang Province, Ningbo, Zhejiang 315300, P.R. China.
Xiaolong GuDepartment of Pulmonology, Ningbo Yinzhou Second Hospital, Ningbo, Zhejiang 315192, P.R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lung adenocarcinoma (LACA) is the leading cause of cancer-associated death worldwide. The present study intended to identify DNA methylation patterns that may serve as diagnostic and prognostic biomarkers for LACA. Data on DNA methylation and the survival data of the patients of LACA were obtained from The Cancer Genome Atlas. Kaplan-Meier curves and receiver operating characteristic curve analysis were utilized to build diagnostic and prognostic models. A total of 13 CpG sites were identified and validated as the optimal diagnostic and prognostic signature for overall survival. It was concluded that the CpG-based signature is a reliable predictor for the diagnosis and prognosis of patients with LACA.

Indexed as

lung adenocarcinomamethylationprognostic signature

Identifiers

PMID31853300
PMCPMC6909784

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.