Evidence map›Paper›PMID 31853261›Full record

ArticleObstetric medicine2019

Rituximab - A novel therapy for severe ITP in pregnancy: A case report.

Fionan Donohoe, Mary Higgins, Shane Higgins, Fionnuala McAuliffe, Karen Murphy

Open access · greenAbstract read
In one paragraph

Article in Obstetric medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.3field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 6 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Fionan DonohoeObstetrics and Gynaecology, National Maternity Hospital, Dublin, Republic of Ireland.
Mary HigginsObstetrics and Gynaecology, National Maternity Hospital, Dublin, Republic of Ireland.
Shane HigginsObstetrics and Gynaecology, National Maternity Hospital, Dublin, Republic of Ireland.
Fionnuala McAuliffeObstetrics and Gynaecology, National Maternity Hospital, Dublin, Republic of Ireland.
Karen MurphyDepartment of Haematology, St Vincent's University Hospital, Dublin, Republic of Ireland.
National Maternity Hospital · IESt. Vincent's University Hospital · IE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRituximab is a novel second-line agent for the treatment of immune thrombocytopenic purpura. Minimal data exist on the use of rituximab in pregnancy. This case illustrates the successful treatment of severe immune thrombocytopenic purpura diagnosed in pregnancy, refractory to all other medical management. CASE: A 32-year-old nulliparous woman was diagnosed with severe immune thrombocytopenic purpura at the time of booking for antenatal care (platelet level of 13 × 10

conclusionRituximab is potentially a safe treatment option for the management of immune thrombocytopenic purpura in pregnancy with good maternal and neonatal outcome when conventional treatments have been unsuccessful. Research is limited to case reports, and therefore limited information currently exists to guide clinicians.

Indexed as

Drugs (medication)haematologyhigh-risk pregnancy

Identifiers

PMID31853261
PMCPMC6909297
OpenAlexW2806302579

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.