ArticleObstetric medicine2019
Hypercalcaemia during pregnancy: Review of maternal and fetal complications, investigations, and management.
Article in Obstetric medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.
- Effects of calcium supplementation on the prevention of preeclampsia: an umbrella review of systematic reviews and meta-analyses.Frontiers in medicine · 2025Pooled it
- Gestational hypercalcemia: a narrative review of literature.Frontiers in medicine · 2026Review
- Turning Points in Cross-Disciplinary Perspective of Primary Hyperparathyroidism and Pancreas Involvements: Hypercalcemia-Induced Pancreatitis,International journal of molecular sciences · 2024Review
- Challenges in the management of hypercalcemia in pregnancy - Case report of two cases.Case reports in women's health · 2024Article
- Expert consensus on multidisciplinary approach to the diagnosis and treatment of primary hyperparathyroidism in pregnancy in China.Endocrine · 2023Article
- Primary hyperparathyroidism in pregnancy: experience of a tertiary centre.Surgery today · 2023Article
- Multidisciplinary team efforts to improve the pregnancy outcome of pregnancy complicated with primary hyperparathyroidism: case series from a single hospital.BMC pregnancy and childbirth · 2021Article
- Primary hyperparathyroidism in pregnancy: observations from the Indian PHPT registry.Journal of endocrinological investigation · 2021Observational
- Primary Hyperparathyroidism in Pregnancy: Literature Review of the Diagnosis and Management.Journal of clinical medicine · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionAsymptomatic mild primary hyperparathyroidism is increasingly being identified during pregnancy. Recent studies have demonstrated inconsistent findings with regard to pregnancy complications and the need for surgical intervention during pregnancy.
methodA retrospective audit of outcomes of pregnancies complicated by hypercalcaemia over a 15-year period was performed.
resultsTwenty-nine pregnancies to 26 women with hypercalcaemia were identified, corresponding to 37 cases per 100,000 deliveries. Hypercalcaemia was due to primary hyperparathyroidism in 90% of cases, with mean serum calcium of 2.89 mmol/l and mean ionised calcium 1.43 mmol/l. Four women underwent successful neck exploration during pregnancy. Pregnancy complications were limited to three cases of pre-eclampsia and one case of symptomatic neonatal hypoparathyroidism.
conclusionClose observation without surgical intervention would seem reasonable in women with mild hypercalcaemia during pregnancy.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.