Evidence map›Paper›PMID 31853235›Full record

ReviewDose-response : a publication of International Hormesis Society

Ethylene Oxide: Cancer Evidence Integration and Dose-Response Implications.

Melissa J Vincent, Jordan S Kozal, William J Thompson, Andrew Maier, G Scott Dotson, Elizabeth A Best, Kenneth A Mundt

Open access · goldAbstract readReview
In one paragraph

Review in Dose-response : a publication of International Hormesis Society. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.5field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 51 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Association of ethylene oxide exposure and obstructive sleep apnea.Environmental health and preventive medicine · 2025
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Potential Carcinogens in Makeup Cosmetics.International journal of environmental research and public health · 2023
    Article
  14. Review
  15. Transitioning to Environmentally Sustainable, Climate-Smart Radiation Oncology Care.International journal of radiation oncology, biology, physics · 2022
    Article
  16. Review
  17. Article
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Melissa J VincentCardno ChemRisk, Cincinnati, OH, USA.
Jordan S KozalCardno ChemRisk, San Francisco, CA, USA.
William J ThompsonCardno ChemRisk, Boston, MA, USA.ORCID https://orcid.org/0000-0002-9457-3234
Andrew MaierCardno ChemRisk, Cincinnati, OH, USA.
G Scott DotsonCardno ChemRisk, Cincinnati, OH, USA.
Elizabeth A BestCardno ChemRisk, Boulder, CO, USA.
Kenneth A MundtCardno ChemRisk, Boston, MA, USA.
Cardno (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The International Agency for Research on Cancer (IARC) and the United States Environmental Protection Agency (USEPA) classified ethylene oxide (EtO) as a known human carcinogen. Critically, both noted that the epidemiological evidence based on lymphoid and breast cancers was "limited," but that the evidence in animal studies was "sufficient" and "extensive" (respectively) and that EtO is genotoxic. The USEPA derived one of the highest published inhalation unit risk (IUR) values (3 × 10

Indexed as

cancerchemicaldose responsemodeling

Identifiers

PMID31853235
PMCPMC6906442
OpenAlexW2995182425

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.