ArticleJournal of pain research2019
Music Reduces Pain Unpleasantness: Evidence from an EEG Study.
Article in Journal of pain research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
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Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it, 39 citations in OpenAlex.
- Effects of white noise on preterm infants in the neonatal intensive care unit: A meta-analysis of randomised controlled trials.Nursing open · 2024Pooled it
- The impact of different music genres on pain tolerance: emphasizing the significance of individual music genre preferences.Scientific reports · 2024Trial
- The Deep-Match Framework for Event-Related Potential Detection in EEG.Sensors (Basel, Switzerland) · 2026Article
- A scoping review of music-based pain treatment mechanism research.Pain reports · 2026Review
- Potential Effects of Music on Non-Motor Symptoms in Parkinson's Disease: Translating Mechanisms to Therapy.Neurology international · 2026Review
- The Predominant Role of Musical Valence Over Arousal in Pain Modulation: A Psychophysiological Study.International journal of psychology : Journal international de psychologie · 2026Article
- Perceived sensorimotor synchrony enhances pain modulation and attenuates laser-evoked potentials.Communications biology · 2025Article
- A comprehensive EEG dataset of laser-evoked potentials for pain research.Scientific data · 2025Article
- Proposed Physiological and Neurobiological Mechanisms of Music's Effect, with a Focus on the Perioperative Period: Literature Evidence from Human, Canine and Feline Medicine.Veterinary sciences · 2025Review
- Effect of auditory interventions on pain in premature infants: a systematic review and meta-analysis.Revista da Associacao Medica Brasileira (1992) · 2025Article
- Music as a perioperative, non-pharmacological intervention in veterinary medicine. Establishing a feasible framework for music implementation and future perspectives with a focus on the perioperative period of dogs and cats.Frontiers in veterinary science · 2025Review
- The psychophysiology of music-based interventions and the experience of pain.Frontiers in psychology · 2024Review
- The Effect of Perioperative Auditory Stimulation with Music on Procedural Pain: A Narrative Review.Current pain and headache reports · 2023Review
- The effect of background liked music on acute pain perception and its neural correlates.Human brain mapping · 2023Article
- Music to My Senses: Functional Magnetic Resonance Imaging Evidence of Music Analgesia Across Connectivity Networks Spanning the Brain and Brainstem.Frontiers in pain research (Lausanne, Switzerland) · 2022Article
- Music-Induced Analgesia in Healthy Participants Is Associated With Expected Pain Levels but Not Opioid or Dopamine-Dependent Mechanisms.Frontiers in pain research (Lausanne, Switzerland) · 2022Article
- Preferred musical attribute dimensions underlie individual differences in music-induced analgesia.Scientific reports · 2021Article
- Neuronal Effects of Listening to Entrainment Music Versus Preferred Music in Patients With Chronic Cancer Pain as Measured via EEG and LORETA Imaging.Frontiers in psychology · 2021Article
- Bibliometric Analysis of Research on the Comorbidity of Pain and Inflammation.Pain research & management · 2021Review
- Pain Modulates Responses to Emotional Stimuli.Frontiers in psychology · 2020Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMusic is sometimes used as an adjunct to pain management. However, there is limited understanding of by what means music modulates pain perception and how the brain responds to nociceptive inputs while listening to music, because clinical practice typically involves the coexistence of multiple therapeutic interventions. To address this challenge, laboratory studies with experimental and control conditions are needed.
methodsIn the present investigation, we delivered nociceptive laser stimuli on 30 participants under three conditions - participants were sitting in silence, listening to their preferred music, or listening to white noise. Differences among conditions were quantified by self-reports of pain intensity and unpleasantness, and brain activity sampled by electroencephalography (EEG).
resultsCompared with the noise and silence conditions, participants in the music condition reported lower ratings on pain unpleasantness, as reflected by reduced brain oscillations immediately prior to the nociceptive laser stimulus at frequencies of 4-15 Hz in EEG. In addition, participants showed smaller P2 amplitudes in laser-evoked potentials (LEPs) when they were listening to music or white noise in comparison to sitting in silence. These findings suggest that a general modulation effect of sounds on pain, with a specific reduction of pain unpleasantness induced by the positive emotional impact.
conclusionMusic may serve as a real-time regulator to modulate pain unpleasantness. Results are discussed in view of current understandings of music-induced analgesia.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.