ArticlePatient preference and adherence2019
Adherence to Statin Therapy and Attainment of LDL Cholesterol Goal Among Patients with Type 2 Diabetes and Dyslipidemia.
Article in Patient preference and adherence, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed.
- Telehealth and challenges of statin adherence in patients with diabetes: a randomized controlled trial.BMC health services research · 2025Trial
- The Complex Interplay Between Dyslipidemic Subjects Living with Type 2 Diabetes and Metabolic Syndrome and Statin Treatment: A Reflection on Adherence and Persistence in the Real World.Diabetes therapy : research, treatment and education of diabetes and related disorders · 2026Article
- CT-Based Visual Atherosclerosis Education Improves Secondary Prevention Adherence: A Retrospective Cohort Study Using Cluster Analysis.Patient preference and adherence · 2026Article
- Factors Related to Suboptimal Adherence to Dyslipidemia Medication: An Exploration Using Nationally Representative Databases.Journal of lipid and atherosclerosis · 2025Article
- The prevalence of gastric reflux symptoms in Saudi Arabian statin-users, and associated factors: a tertiary-center cross-sectional observational study.Annals of medicine and surgery (2012) · 2025Article
- Lipid Control and Social Determinants: Their Association With LDL and Non-HDL Cholesterol Goals in Older Adults-A Population-Based Study.Clinical cardiology · 2025Article
- Suitability of Measures of Pharmacy-Based Medication Adherence for Routine Clinical Use Among Patients with Chronic Diseases: A Systematic Review.Patient preference and adherence · 2025Review
- Lipid management strategies for diabetic patients align with an evidence-based guideline.Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences · 2024Article
- Projected Cost Savings With Optimal Medication Adherence in Patients With Cardiovascular Disease Requiring Lipid-Lowering Therapy: A Multinational Economic Evaluation Study.Journal of the American Heart Association · 2024Article
- Adherence to Statin Among Diabetic Patients in Diabetic Centers in Qassim Region, Saudi Arabia.Cureus · 2023Article
- Patient journey for hypertension and dyslipidemia in Saudi Arabia: highlighting the evidence gaps.Archives of public health = Archives belges de sante publique · 2023Article
- Factors Affecting Adherence to Lipid-lowering Drugs: A Scoping Review.Oman medical journal · 2023Article
- Challenges in Improving Adherence to Diet and Drug Treatment in Hypercholesterolemia Patients.International journal of environmental research and public health · 2023Review
- Physicians' misperceived cardiovascular risk and therapeutic inertia as determinants of low LDL-cholesterol targets achievement in diabetes.Cardiovascular diabetology · 2022Article
- Prevalence of traditional cardiovascular risk factors for coronary artery disease and elevated fibrinogen among active military personnel in Republic of Serbia: A cross-sectional study.Journal of medical biochemistry · 2022Article
- Prevalence, patterns and determinants of dyslipidaemia among South African adults with comorbidities.Scientific reports · 2022Article
- Improving statin treatment strategies to reduce LDL-cholesterol: factors associated with targets' attainment in subjects with and without type 2 diabetes.Cardiovascular diabetology · 2021Article
- Evaluation of oxidative stress levels in obesity and diabetes by the free oxygen radical test and free oxygen radical defence assays and correlations with anthropometric and laboratory parameters.World journal of diabetes · 2020Article
- Dyslipidemia: A Trigger for Coronary Heart Disease in Romanian Patients with Diabetes.Metabolites · 2020Article
- Long-Term Benefit and Withdrawal Effect of Statins After Percutaneous Coronary Intervention: A Nationwide Population-Based Cohort Study.Patient preference and adherence · 2020Article
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundStatins are widely utilized antidyslipidemics with a proven track record of safety and efficacy. However, the efficacy of these therapeutic agents hinges on patients' adherence to their prescribed statins.
objectiveThe primary objectives of this study were to examine the relationship between adherence to prescribed statins and its impact on the low-density lipoprotein (LDL) level, and to explore the factors that influence patient adherence to statins among patients with diabetes and dyslipidemia.
methodsThis was a retrospective, cross-sectional study using the electronic health records data of adults (≥18 years) with type 2 diabetes and dyslipidemia visiting outpatient clinics at a university-affiliated tertiary care center. Adherence to statin therapy was estimated using the proportion of days covered (PDC). Patients with diabetes were considered adherent to statins if they had a PDC of ≥80%. Treatment success was considered if the LDL level of < 2.6 mmol/L.
resultsOut of 10,226 of patients with diabetes, 1532 met the inclusion criteria and were included in the study. Seventy-nine percent of the patients with diabetes were on atorvastatin and 21% were on simvastatin. The vast majority of the patients with diabetes (77%) were considered adherent and about 42% achieved LDL-cholesterol goal < 2.6 mmol/L. No association between adherence to statin therapy and LDL goal attainment was observed. Women had lower odds of being adherent to statin therapy (AOR=0.66, 95% CI: 0.49-0.87) compared to men. Further, young adults (18-44 years) had lower odds of being adherent to statin therapy (AOR=0.58, 95% CI: 0.32-0.97) compared to older adults (age>65 years).
conclusionThe findings of this study highlight the need to examine the impact of adherence to statins on healthcare services utilization due to different complications of uncontrolled dyslipidemia.
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