ArticleHypertension research : official journal of the Japanese Society of Hypertension2020
Brachial-ankle pulse wave velocity in healthy Japanese adolescents: reference values for the assessment of arterial stiffness and cardiovascular risk profiles.
Article in Hypertension research : official journal of the Japanese Society of Hypertension, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 24 citations in OpenAlex.
- Central blood pressure lowering effect of telmisartan-rosuvastatin single-pill combination in hypertensive patients combined with dyslipidemia: A pilot study.Journal of clinical hypertension (Greenwich, Conn.) · 2021Trial
- Comparisons of prognostic value between brachial-ankle pulse wave velocity and estimated pulse wave velocity.Hypertension research : official journal of the Japanese Society of Hypertension · 2026Article
- Cardiovascular Risk Stratification in Youth-Onset Type 2 Diabetes Using Machine Learning.Journal of Korean medical science · 2026Article
- Longitudinal associations between body fat mass and cardiovascular outcomes among Chinese children: mediation by cardiometabolic risk factors.BMC medicine · 2026Article
- Pulse Wave Velocity Progression Determinants: No Significant Association with Novel Lipids Parameter.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2025Article
- Comparison between vascular age based on brachial-ankle pulse wave velocity or carotid-femoral pulse wave velocity.Hypertension research : official journal of the Japanese Society of Hypertension · 2025Article
- Mesenchymal Stem Cell Therapy for Hutchinson-Gilford Progeria: Improvements in Arterial Stiffness and Bone Mineral Density in a Single Case.Children (Basel, Switzerland) · 2025Article
- Pulse Wave Velocity of 8.2 m/s as a Threshold Associated with Cardiovascular Target Organ Damage Presence.Arquivos brasileiros de cardiologia · 2023Article
- Atherosclerosis and arteriosclerosis.Hypertension research : official journal of the Japanese Society of Hypertension · 2023Article
- Association between brachial-ankle pulse wave velocity and microvascular complications in type 2 diabetes mellitus.BMC endocrine disorders · 2023Article
- The Impact of the Blood Lipids Levels on Arterial Stiffness.Journal of cardiovascular development and disease · 2023Review
- Microvascular reactivity using laser Doppler measurement in type 2 diabetes with subclinical atherosclerosis.Lasers in medical science · 2023Article
- Dendritic cells as potential initiators of immune-mediated hypertensive disorders.Hypertension research : official journal of the Japanese Society of Hypertension · 2022Article
- Association between remnant cholesterol and arterial stiffness: A secondary analysis based on a cross-sectional study.Journal of clinical hypertension (Greenwich, Conn.) · 2022Article
- Reference values of office central blood pressure, pulse wave velocity, and augmentation index recorded by means of the Mobil-O-Graph PWA monitor.Hypertension research : official journal of the Japanese Society of Hypertension · 2020Article
- State of the Art Review: Brachial-Ankle PWV.Journal of atherosclerosis and thrombosis · 2020Review
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Brachial-ankle pulse wave velocity (baPWV) has been used as a simple and convenient method of evaluating arterial stiffness and is considered useful for screening subclinical vascular damage in primary care settings and in large populations. The aim of this study was to determine the reference values of baPWV in adolescents based on age and sex to evaluate and classify vascular abnormalities in this age population. Noninvasive baPWV measurements using an oscillometric device were carried out in 5936 participants aged 12-18 years who had no history of syndromic obesity, hypertension, dyslipidemia, diabetes mellitus, or renal disease. Of these, we extracted data from 4524 healthy adolescents free from atherosclerotic risk factors and constructed sex-specific reference percentiles normalized to age using the LMS method. The baPWV increased with age and was significantly higher in males than in females. Multivariate regression analysis demonstrated that age, body mass index, and blood pressure were the major determinants of baPWV for both males and females. Among a sample of 3825 adolescents, including individuals with risk factors, the prevalence of central obesity, raised blood pressure, raised triglycerides, reduced high-density lipoprotein cholesterol, and impaired fasting glycemia significantly increased along with the standardized baPWV z-score level. In addition, there was a graded nature regarding the association between the baPWV z-score and the clustering number of the metabolic syndrome components. These results suggest that the proposed reference values of baPWV could help classify vascular abnormalities of adolescents caused by the presence of risk factors and thereby contribute to determining individuals with cardiovascular risk in this age population.
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