Evidence map›Paper›PMID 31852960›Full record

ArticleScientific reports2019

Differences in lung cancer characteristics and mortality rate between screened and non-screened cohorts.

Fu-Zong Wu, Pei-Lun Kuo, Yi-Luan Huang, En-Kuei Tang, Chi-Shen Chen, Ming-Ting Wu, Yun-Pei Lin

Erratum issuedAbstract read
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

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  16. Observational
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  19. 9G TestCancers · 2020
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Fu-Zong WuDepartment of Radiology, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan.
Pei-Lun KuoFaculty of Medicine, School of Medicine, National Yang Ming University, Taipei, Taiwan.
Yi-Luan HuangDepartment of Radiology, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan.
En-Kuei TangDepartment of Surgery, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan.
Chi-Shen ChenPhysical Examination Center, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan.
Ming-Ting WuDepartment of Radiology, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan.
Yun-Pei LinDepartment of Radiology, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan. fc760203@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Screening programs for lung cancer aim to allow diagnosis at the early stage, and therefore the decline in mortality rates. Thus, the aim of this retrospective cohort study was to the comparison of screened and non-screened lung cancer in terms of lung cancer characteristics, overdiagnosis and survival rate. A retrospective study in which 2883 patients with 2883 lung cancer diagnosed according to the hospital-based lung cancer register database between 2007 and 2017. A comparison was performed in term of clinical characteristics and outcomes of lung cancer between the screened and non-screening patient groups. 2883 subjects were identified (93 screened and 2790 non-screened). Screened group patients were younger (59.91 ± 8.14 versus 67.58 ± 12.95; p < 0.0001), and were more likely to be female than non-screened group (61.3% versus 36.8%; p < 0.0001). The screened group showed significantly better outcomes in overall mortality than the non-screened group (10.75% versus 79.06%; <0.0001). In a Cox proportional hazard model, lung cancer in the screened group proved to be an independent prognostic factor in lung cancer subjects. Our findings point to the improved survival outcome in the screened group and might underline the benefit of low-dose computed tomography (LDCT) screening program in Asian populations with the high prevalence of non-smoking-related lung cancer. Further study aimed at the LDCT mass screening program targeting at light smokers and non-smoker outside of existing screening criteria is warranted.

Indexed as

Early Detection of CancerAgedDisease-Free SurvivalFemaleHumansLungLung NeoplasmsMaleMass ScreeningMiddle AgedPrevalenceRetrospective StudiesSmokersSurvival RateTomography, X-Ray Computed

Identifiers

PMID31852960
PMCPMC6920422

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.