ArticleScientific reports2019
Schizophyllum commune induces IL-17-mediated neutrophilic airway inflammation in OVA-induced asthma model mice.
Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 13 citations in OpenAlex.
- The lung microbiome and asthma: from inflammatory phenotype differentiation to microbe-based immunomodulatory strategies.Frontiers in immunology · 2026Review
- Effects of human umbilical cord blood mononuclear cells on ovalbumin-induced asthma in mice.Journal of thoracic disease · 2023Article
- Immunologic, genetic, and ecological interplay of factors involved in allergic diseases.Frontiers in allergy · 2023Review
- Chronic allergic asthma alters m6A epitranscriptomic tagging of mRNAs and lncRNAs in the lung.Bioscience reports · 2022Article
- Influence of the early-life gut microbiota on the immune responses to an inhaled allergen.Mucosal immunology · 2022Article
- Dynamic Changes of NCRInflammation · 2022Article
- Blockade of protease-activated receptor 2 attenuates allergenmediated acute lung inflammation and leukocyte recruitment in mice.Journal of biosciences · 2022Article
- The Fermented Soy Product ImmuBalanceNutrients · 2021Article
- Role of liver-X-receptors in airway remodeling in mice with chronic allergic asthma.Experimental and therapeutic medicine · 2021Article
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Schizophyllum commune is a ubiquitous basidiomycetous fungus typically found across the world, which has been detected in indoor and outdoor air. Some studies indicated that sensitization to S. commune is correlated with asthma severity in patients. Patients with chronic severe or acute fatal asthma have neutrophil-dominant airway inflammation. We hypothesized that S. commune can exacerbate asthma. To test this hypothesis, we evaluated the direct immunomodulatory activities of S. commune in allergic airway inflammation induced by non-fungal sensitization. Ovalbumin (OVA)-induced asthma model mice were generated using wild-type (WT) and Il-17a
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Registered trials
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