ArticleScience translational medicine2019
Elite control of HIV is associated with distinct functional and transcriptional signatures in lymphoid tissue CD8
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Article in Science translational medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 83 papers.
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83citing papers in PubMed
8.0field-weighted citation impact, top 2% of its field
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Who cites it
83 citing papers in PubMed, 123 citations in OpenAlex.
- Epigenetic scars of CD8Nature immunology · 2021Trial
- Article
- HIV cure: from early therapies to cutting-edge strategies.Journal of neurovirology · 2026Review
- A Versatile Anti-CXCR5 Monoclonal Antibody (CxCurrent issues in molecular biology · 2026Article
- Immunometabolic Modulation of the Bone Marrow Niche by Bioactive Materials to Rescue Impaired Fracture Healing.Stem cell reviews and reports · 2026Review
- Viral load-driven systemic immune exhaustion is an enabler of antibody breadth in HIV infection.bioRxiv : the preprint server for biology · 2026Article
- HIV controllers, lessons learnt from the lymphoid tissues.Current opinion in HIV and AIDS · 2026Review
- Recapitulating the qualities of HIV-specific CD8 + T cells from spontaneous controllers.Current opinion in HIV and AIDS · 2026Review
- Early immune responses anticipate HIV rebound and precede viral control.bioRxiv : the preprint server for biology · 2026Article
- Fine-tuning BACH2 dosage balances stemness and effector function to enhance antitumor T cell therapy.Nature immunology · 2026Article
- CXCR5 identifies stem-like resident memory CD8⁺ T cells enriched for latent EBV specificity in tonsils.Science advances · 2026Article
- Roadmap for spatial transcriptomics of HIV in tissues.Current opinion in HIV and AIDS · 2025Review
- Therapeutic CD8Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Novel insights into immune checkpoints in HIV/SHIV infection: from SHIVJournal of virology · 2025Article
- Advances in Single-Cell Sequencing for Infectious Diseases: Progress and Perspectives.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Review
- Evaluating cell cycle- and autophagy-associated cellular accumulation of lipid-based nanoparticles.Nature communications · 2025Article
- T cell-derived small extracellular vesicles in cancer-immune interactions.Cancer immunology, immunotherapy : CII · 2025Review
- Application of mass cytometry in the immune microenvironment of breast cancer.Medical oncology (Northwood, London, England) · 2025Review
- Early treatment and PD1 inhibition enhance HIV-specific functionality of follicular CD8+ T cells.JCI insight · 2025Article
- Deep immunophenotyping reveals circulating activated lymphocytes in individuals at risk for rheumatoid arthritis.The Journal of clinical investigation · 2025Article
23 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
23 authors at 10 institutions in 4 countries.
Son NguyenDepartment of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.ORCID 0000-0002-0475-5158
Claire DeleageAIDS and Cancer Virus Program, Frederick National Laboratory for Cancer Research, Leidos Biomedical Research Inc., Frederick, MD 21702, USA.ORCID 0000-0002-3507-0055
Samuel DarkoHuman Immunology Section, Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.ORCID 0000-0002-9711-8122
Amy RansierHuman Immunology Section, Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.
Duc P TruongDepartment of Mathematics, Southern Methodist University, Dallas, TX 75205, USA.ORCID 0000-0002-9806-3274
Divyansh AgarwalDepartment of Statistics, University of Pennsylvania, Philadelphia, PA 19104, USA.ORCID 0000-0003-0404-6877
Alberto Sada JappDepartment of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.ORCID 0000-0001-8106-8987
Vincent H WuDepartment of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.ORCID 0000-0002-8640-6065
Leticia Kuri-CervantesDepartment of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.ORCID 0000-0002-2432-9500
Mohamed Abdel-MohsenThe Wistar Institute, Philadelphia, PA 19104, USA.ORCID 0000-0002-9945-4314
Perla M Del Rio EstradaDepartamento de Investigación en Enfermedades Infecciosas, Instituto Nacional de Enfermedades Respiratorias, Mexico City 14080, Mexico.ORCID 0000-0003-3366-3268
Yuria Ablanedo-TerrazasDepartamento de Investigación en Enfermedades Infecciosas, Instituto Nacional de Enfermedades Respiratorias, Mexico City 14080, Mexico.
Emma GostickDivision of Infection and Immunity, Cardiff University School of Medicine, Cardiff CF14 4XN, UK.ORCID 0000-0002-3628-5824
James A HoxieDepartment of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.ORCID 0000-0002-6257-4902
Nancy R ZhangDepartment of Statistics, University of Pennsylvania, Philadelphia, PA 19104, USA.ORCID 0000-0002-0880-5749
Ali NajiDepartment of Surgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.ORCID 0000-0002-6926-3306
Gustavo Reyes-TeránDepartamento de Investigación en Enfermedades Infecciosas, Instituto Nacional de Enfermedades Respiratorias, Mexico City 14080, Mexico.ORCID 0000-0001-7295-8240
Jacob D EstesVaccine and Gene Therapy Institute, Oregon Health and Science University, Portland, OR 97239, USA.ORCID 0000-0002-9652-6394
David A PriceDivision of Infection and Immunity, Cardiff University School of Medicine, Cardiff CF14 4XN, UK.ORCID 0000-0001-9416-2737
Daniel C DouekHuman Immunology Section, Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.
Steven G DeeksDepartment of Medicine, University of California, San Francisco General Hospital, San Francisco, CA 94110, USA.ORCID 0000-0001-6371-747X
Marcus BuggertDepartment of Medicine Huddinge, Karolinska Institutet, Karolinska University Hospital Huddinge, 14186 Stockholm, Sweden.ORCID 0000-0003-0633-1719
Michael R BettsDepartment of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA. betts@pennmedicine.upenn.edu.ORCID 0000-0002-7690-1484
University of Pennsylvania · USInstituto Nacional de Enfermedades Respiratorias · MXNational Institutes of Health · USCardiff University · GBKarolinska University Hospital · SELeidos (United States) · USOregon National Primate Research Center · USSan Francisco General Hospital · USSouthern Methodist University · USThe Wistar Institute · US
Funding
Upgrade of confocal microscopy at the Oregon National Primate Research CenterP51OD011092 · OD · OREGON HEALTH & SCIENCE UNIVERSITY · PI Bonnie J. Nagel · 2012 to 2026
$203.9MVirology CoreP30AI027763 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI STEVEN Grant DEEKS · 1988 to 2026
$93.6MVirus & Reservoirs CoreP30AI045008 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI ROBERT GROSS · 1999 to 2026
$78.6MFirst-in-human study of two anti-SARS CoV-2 antibodies in health volunteersUM1AI126620 · NIAID · WISTAR INSTITUTE · PI MONTANER, LUIS J, RILEY, JAMES L. · 2016 to 2021
$24.5MT cell functionality and control of HIV infectionR01AI076066 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI BETTS, MICHAEL R · 2008 to 2017
$4.6MRole of Intestinal Barrier Integrity in Modulating the Host Glycome During COVID-19R01DK123733 · NIDDK · WISTAR INSTITUTE · PI ABDEL MOHSEN, MOHAMED, KESHAVARZIAN, ALI · 2020 to 2024
$4.5MViral control mechanisms of HIV-specific T cells in HIV-infected lymph nodeR01AI118694 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI BETTS, MICHAEL R · 2015 to 2019
$3.3MSialic Acid Modulation of HIV-associated Chronic InflammagingR01AG062383 · NIA · WISTAR INSTITUTE · PI ABDEL MOHSEN, MOHAMED · 2019 to 2023
$3.0MExploring Cell-free Glycomic Interactions in HIV-associated Neurological DisordersR21NS106970 · NINDS · WISTAR INSTITUTE · PI ABDEL MOHSEN, MOHAMED, NDHLOVU, LISHOMWA C · 2017 to 2018
$507kRole of Host Glycosylation in the Galectin-9-Mediated Reversal of HIV LatencyR21AI129636 · NIAID · WISTAR INSTITUTE · PI ABDEL MOHSEN, MOHAMED · 2017 to 2018
$496kHost Glycomic Determinants of HIV Persistence in vivoR21AI143385 · NIAID · WISTAR INSTITUTE · PI ABDEL MOHSEN, MOHAMED · 2019 to 2020
$491kNIAID NIH HHS P30 AI027763NIAID NIH HHS P30 AI045008NIAID NIH HHS R01 AI076066NIAID NIH HHS R01 AI118694NIAID NIH HHS R21 AI129636NIAID NIH HHS R21 AI143385NIAID NIH HHS UM1 AI126620NIH HHS P51 OD011092Wellcome TrustWellcome Trust 100326/Z/12/Z
Abstract
The functional properties of circulating CD8
Indexed as
CD4-Positive T-LymphocytesCD8-Positive T-LymphocytesHIV-1HIV InfectionsHumansLymphoid TissueViral Load
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.