Evidence map›Paper›PMID 31852787›Full record

ArticleJournal of virology2020

The Severe Fever with Thrombocytopenia Syndrome Virus NSs Protein Interacts with CDK1 To Induce G

Sihua Liu, Hongyun Liu, Jun Kang, Leling Xu, Keke Zhang, Xueping Li, Wen Hou, Zhiyun Wang, Tao Wang

Open access · greenAbstract read
In one paragraph

Article in Journal of virology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 46 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Sihua LiuSchool of Life Sciences, Tianjin University, Tianjin, China.
Hongyun LiuSchool of Life Sciences, Tianjin University, Tianjin, China.
Jun KangSchool of Life Sciences, Tianjin University, Tianjin, China.
Leling XuSchool of Life Sciences, Tianjin University, Tianjin, China.
Keke ZhangSchool of Life Sciences, Tianjin University, Tianjin, China.
Xueping LiSchool of Life Sciences, Tianjin University, Tianjin, China.
Wen HouKey Laboratory of Transplantation of Chinese Academy of Medical Sciences, Tianjin First Central Hospital, Tianjin, China.
Zhiyun WangSchool of Environmental Science and Engineering, Tianjin University, Tianjin, China zhiyun_wang@tju.edu.cn wangtaobio@tju.edu.cn.
Tao WangSchool of Life Sciences, Tianjin University, Tianjin, China zhiyun_wang@tju.edu.cn wangtaobio@tju.edu.cn.
Tianjin University · CNTianjin Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Severe fever with thrombocytopenia syndrome virus (SFTSV) is a newly identified phlebovirus associated with severe hemorrhagic fever in humans. While many viruses subvert the host cell cycle to promote viral growth, it is unknown whether this is a strategy employed by SFTSV. In this study, we investigated how SFTSV manipulates the cell cycle and the effect of the host cell cycle on SFTSV replication. Our results suggest that cells arrest at the G

Indexed as

G2 Phase Cell Cycle CheckpointsVirus ReplicationBunyaviridae InfectionsCDC2 Protein KinaseCyclin B1HEK293 CellsHeLa CellsHep G2 CellsHumansPhlebovirusViral Nonstructural ProteinsCCNB1 protein, humanCDC2 Protein KinaseCDK1 protein, humanCyclin B1Viral Nonstructural Proteinscell cyclecyclin B1-CDK1 complexG2/M arrestSFTSV

Identifiers

PMID31852787
PMCPMC7158732
OpenAlexW2996419786

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.