Evidence map›Paper›PMID 31852784›Full record

ArticleJournal of virology2020

CXCR4-Using HIV Strains Predominate in Naive and Central Memory CD4

Michael Roche, Carolin Tumpach, Jori Symons, Matthew Gartner, Jenny L Anderson, Gabriela Khoury, Kieran Cashin, Paul U Cameron, Melissa J Churchill, Steven G Deeks and 2 more

Open access · greenAbstract read
In one paragraph

Article in Journal of virology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 20 citations in OpenAlex.

  1. Trial
  2. HCV-specific CD4EBioMedicine · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Distinct memory CD4ASM case reports · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Observational
  12. Article
  13. Article
  14. Virologie (Montrouge, France) · 2022
    Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 2 countries.

Michael RocheThe Peter Doherty Institute for Infection and Immunity, University of Melbourne and Royal Melbourne Hospital, Melbourne, Australia.
Carolin TumpachThe Peter Doherty Institute for Infection and Immunity, University of Melbourne and Royal Melbourne Hospital, Melbourne, Australia.
Jori SymonsThe Peter Doherty Institute for Infection and Immunity, University of Melbourne and Royal Melbourne Hospital, Melbourne, Australia.
Matthew GartnerSchool of Health and Biomedical Sciences, RMIT University, Bundoora, Australia.
Jenny L AndersonThe Peter Doherty Institute for Infection and Immunity, University of Melbourne and Royal Melbourne Hospital, Melbourne, Australia.
Gabriela KhouryThe Peter Doherty Institute for Infection and Immunity, University of Melbourne and Royal Melbourne Hospital, Melbourne, Australia.
Kieran CashinSchool of Health and Biomedical Sciences, RMIT University, Bundoora, Australia.
Paul U CameronThe Peter Doherty Institute for Infection and Immunity, University of Melbourne and Royal Melbourne Hospital, Melbourne, Australia.ORCID 0000-0002-1906-6945
Melissa J ChurchillSchool of Health and Biomedical Sciences, RMIT University, Bundoora, Australia.
Steven G DeeksDepartment of Medicine, University of California, San Francisco, California, USA.
Paul R GorrySchool of Health and Biomedical Sciences, RMIT University, Bundoora, Australia.
Sharon R LewinThe Peter Doherty Institute for Infection and Immunity, University of Melbourne and Royal Melbourne Hospital, Melbourne, Australia sharon.lewin@unimelb.edu.au.
The Royal Melbourne Hospital · AURMIT University · AUUniversity of California, San Francisco · US

Funding

Virology CoreP30AI027763 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI STEVEN Grant DEEKS · 1988 to 2026
$93.6M
NIAID NIH HHS P30 AI027763NIMHD NIH HHS L60 MD003100
6 · The paper itself

Abstract

HIV can persist in people living with HIV (PLWH) on antiretroviral therapy (ART) in multiple CD4

Indexed as

HIV InfectionsAnti-Retroviral AgentsCD4-Positive T-LymphocytesHEK293 CellsHIV-1HumansImmunologic MemoryReceptors, CXCR4Virus LatencyAnti-Retroviral AgentsCXCR4 protein, humanReceptors, CXCR4CCR5CXCR4HIVlatencytropism

Identifiers

PMID31852784
PMCPMC7158712
OpenAlexW2995700911

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.