Evidence map›Paper›PMID 31852778›Full record

ArticleJournal of virology2020

Use of a Glycan Library Reveals a New Model for Enteric Virus Oligosaccharide Binding and Virion Stabilization.

Hua Lu, Mark A Lehrman, Julie K Pfeiffer

Open access · greenAbstract read
In one paragraph

Article in Journal of virology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. A single mutation in an enteric virus alters tropism and sensitivity to microbiota.Proceedings of the National Academy of Sciences of the United States of America · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Hua LuDepartment of Microbiology, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Mark A LehrmanDepartment of Pharmacology, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Julie K PfeifferDepartment of Microbiology, University of Texas Southwestern Medical Center, Dallas, Texas, USA Julie.Pfeiffer@utsouthwestern.edu.
The University of Texas Southwestern Medical Center · US

Funding

The influence of host barriers on viral quasispecies diversity and pathogenesisR01AI074668 · NIAID · UT SOUTHWESTERN MEDICAL CENTER · PI PFEIFFER, JULIE K · 2008 to 2022
$6.0M
The N-Glycosylation Pathway And Signaling By Free Mannose-6-PhosphateR01GM038545 · NIGMS · UT SOUTHWESTERN MEDICAL CENTER · PI LEHRMAN, MARK · 1987 to 2017
$5.7M
Enteric virus-microbiota interactionsR37AI074668 · NIAID · UT SOUTHWESTERN MEDICAL CENTER · PI Julie K Pfeiffer · 2023 to 2026
$2.5M
N-Glycosylation And ER StressR56GM038545 · NIGMS · UT SOUTHWESTERN MEDICAL CENTER · PI LEHRMAN, MARK · 2008 to 2008
$385k
Howard Hughes Medical InstituteNIAID NIH HHS R01 AI074668NIAID NIH HHS R37 AI074668NIGMS NIH HHS R01 GM038545NIGMS NIH HHS R56 GM038545
6 · The paper itself

Abstract

Enteric viruses infect the gastrointestinal tract, and bacteria can promote replication and transmission of several enteric viruses. Viruses can be inactivated by exposure to heat or bleach, but poliovirus, coxsackievirus B3, and reovirus can be stabilized by bacteria or bacterial polysaccharides, limiting inactivation and aiding transmission. We previously demonstrated that certain

Indexed as

PolysaccharidesAnimalsBacteriaCapsid ProteinsChlorocebus aethiopsEnterovirusEnterovirus InfectionsHeLa CellsHumansLipopolysaccharidesOligosaccharidesPoliovirusVero CellsVirionCapsid ProteinsLipopolysaccharidesOligosaccharidesPolysaccharidesenteric virusglycovirologypoliovirusvirion stability

Identifiers

PMID31852778
PMCPMC7158723
OpenAlexW2994663578

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.