Evidence map›Paper›PMID 31852725›Full record

ArticleGenetics2020

Antioxidant CoQ10 Restores Fertility by Rescuing Bisphenol A-Induced Oxidative DNA Damage in the

Maria Fernanda Hornos Carneiro, Nara Shin, Rajendiran Karthikraj, Fernando Barbosa, Kurunthachalam Kannan, Monica P Colaiácovo

Open access · bronzeAbstract read
In one paragraph

Article in Genetics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 39 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Microplastic-Mediated Delivery of Di-butyl Phthalate AltersMicroplastics (Basel, Switzerland) · 2025
    Article
  4. Coenzyme Q10 and Xenobiotic Metabolism: An Overview.International journal of molecular sciences · 2025
    Review
  5. Exploring the protective effects of coenzyme Q10 on female fertility.Frontiers in cell and developmental biology · 2025
    Review
  6. Article
  7. Review
  8. Review
  9. Does Coenzyme Q10 Supplementation Improve Human Oocyte Quality?International journal of molecular sciences · 2021
    Review
  10. Review
  11. Article
  12. Review
  13. Mitochondrial Epigenetics and Environmental Health: Making a Case for Endocrine Disrupting Chemicals.Toxicological sciences : an official journal of the Society of Toxicology · 2020
    Review
  14. Genome-Protecting Compounds as Potential Geroprotectors.International journal of molecular sciences · 2020
    Review
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Maria Fernanda Hornos Carneiro *Department of Genetics, Harvard Medical School, Boston, Massachusetts 02115.
Nara Shin *Department of Genetics, Harvard Medical School, Boston, Massachusetts 02115.ORCID 0000-0002-9910-4971
Rajendiran KarthikrajWadsworth Center, New York State Department of Health, Albany, New York 12201.ORCID 0000-0001-9680-8079
Fernando BarbosaSchool of Pharmaceutical Sciences of Ribeirao Preto, Universidade de Sao Paulo, 14040-903, Brazil.
Kurunthachalam KannanWadsworth Center, New York State Department of Health, Albany, New York 12201.
Monica P ColaiácovoDepartment of Genetics, Harvard Medical School, Boston, Massachusetts 02115 mcolaiacovo@genetics.med.harvard.edu.ORCID 0000-0001-7803-4372
Harvard University · USWadsworth Center · USUniversidade de São Paulo · BR

Funding

Enhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Ann E. Rougvie · 2012 to 2026
$7.5M
NIH HHS P40 OD010440
6 · The paper itself

Abstract

Endocrine-disrupting chemicals are ubiquitously present in our environment, but the mechanisms by which they adversely affect human reproductive health and strategies to circumvent their effects remain largely unknown. Here, we show in

Indexed as

AnimalsAntioxidantsBenzhydryl CompoundsBisphenol A CompoundsCaenorhabditis elegansCaenorhabditis elegans ProteinsDNA DamageDNA RepairFertilityGerm CellsGerm-Line MutationMitochondriaOocytesOxidation-ReductionOxidative StressPhenolsAntioxidantsBenzhydryl Compoundsbisphenol ABisphenol A CompoundsCaenorhabditis elegans Proteinscoenzyme Q10PhenolsReactive Oxygen SpeciesUbiquinoneBisphenol AC. elegansCoenzyme Q10germlinemeiosis

Identifiers

PMID31852725
PMCPMC7017011
OpenAlexW2995984512

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.