ArticleJournal of the American Society of Nephrology : JASN2020
Early Steroid Withdrawal in Deceased-Donor Kidney Transplant Recipients with Delayed Graft Function.
Article in Journal of the American Society of Nephrology : JASN, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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20 citing papers in PubMed, 31 citations in OpenAlex.
- Effectiveness and safety of denosumab on osteoporosis treatment in kidney transplant recipients.Kidney research and clinical practice · 2026Article
- Cost Impact of a Novel Pre-transplant Risk Assessment Tool for Early Acute Rejection in Kidney Transplant Patients.Journal of health economics and outcomes research · 2026Article
- Twenty-Year Kidney Transplant Outcomes With Prednisone-Free Maintenance Immunosuppression: A Matched Control Analysis.Clinical transplantation · 2025Article
- Steroid Avoidance With Low-Dose Tacrolimus is Safe and Effective in the Long-Term for Kidney Transplant Recipients.Kidney international reports · 2025Article
- From Risk Assessment to Management: Cardiovascular Complications in Pre- and Post-Kidney Transplant Recipients: A Narrative Review.Diagnostics (Basel, Switzerland) · 2025Review
- Early Steroid Withdrawal in Kidney Transplant Recipients: PRO.Kidney360 · 2025Article
- Early Steroid Withdrawal in Kidney Transplant Recipients: CON.Kidney360 · 2025Article
- Precision in Immune Management: Balancing Steroid Exposure, Rejection Risk, and Infectious Outcomes in Adult Kidney Transplant Recipients.Journal of personalized medicine · 2024Article
- Safety and metabolic advantages of steroid withdrawal after 6 months posttransplant in de novo kidney transplantation: A 1-year prospective cohort study.Immunity, inflammation and disease · 2022Article
- HOPE in action: A prospective multicenter pilot study of liver transplantation from donors with HIV to recipients with HIV.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2022Article
- Effect of Early Steroid Withdrawal on Posttransplant Diabetes Among Kidney Transplant Recipients Differs by Recipient Age.Transplantation direct · 2022Article
- The Risk of Postkidney Transplant Outcomes by Induction Choice Differs by Recipient Age.Transplantation direct · 2021Article
- Changes in cancer incidence and outcomes among kidney transplant recipients in the United States over a thirty-year period.Kidney international · 2021Article
- Clinical Relevance of Corticosteroid Withdrawal on Graft Histological Lesions in Low-Immunological-Risk Kidney Transplant Patients.Journal of clinical medicine · 2021Article
- Delayed graft function and acute rejection following HLA-incompatible living donor kidney transplantation.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2021Article
- Early steroid withdrawal in HIV-infected kidney transplant recipients: Utilization and outcomes.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2021Article
- Inconsistencies in the association of clinical factors with the choice of early steroid withdrawal across kidney transplant centers: A national registry study.Clinical transplantation · 2021Article
- Kinetic GFR Outperforms CKD-EPI for Slow Graft Function Prediction in the Immediate Postoperative Period Following Kidney Transplantation.Journal of clinical medicine · 2020Article
- A case of successful late steroid withdrawal after ABO-incompatible kidney transplantation.Korean journal of transplantation · 2020Article
- When Less Becomes More: Life and Losses without the 'Roids'?Journal of the American Society of Nephrology : JASN · 2020Article
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9 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundEarly steroid withdrawal (ESW) is associated with acceptable outcomes in kidney transplant (KT) recipients. Recipients with delayed graft function (DGF), however, often have a suboptimal allograft milieu, which may alter the risk/benefit equation for ESW. This may contribute to varying practices across transplant centers.
methodsUsing the Scientific Registry of Transplant Recipients, we studied 110,019 adult deceased-donor KT recipients between 2005 and 2017. We characterized the association of DGF with the use of ESW versus continued steroid maintenance across KT centers, and quantified the association of ESW with acute rejection, graft failure, and mortality using multivariable logistic and Cox regression with DGF-ESW interaction terms.
resultsOverall 29.2% of KT recipients underwent ESW. Recipients with DGF had lower odds of ESW (aOR=
conclusionsKT centers in the United States use ESW inconsistently in recipients with DGF. Our findings suggest ESW may lead to worse KT outcomes in recipients with DGF.
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