Evidence map›Paper›PMID 31852650›Full record

Trial reportNan fang yi ke da xue xue bao = Journal of Southern Medical University2019

[Efficacy and safety of early physical therapy for acute gastrointestinal injury during mechanical ventilation in patients with sepsis: a randomized controlled pilot trial].

Danlei Liu, Zhouqian Xu, Changchun Qu, Baoshan Huo, Hanqi Lai, Yang Li, Bin Liu, Huojin Deng, Qianwen Wang, Dujuan Li and 3 more

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 4 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 7 institutions in 1 country.

Danlei LiuDepartment of Intensive Care Medicine, Zhujiang Hospital, Southern Medical University, Guangzhou 510282, China.
Zhouqian XuDepartment of Intensive Care Medicine, Huaduo Hospital Affiliated to Southern Medical University, Guangzhou 510800, China.
Changchun QuDepartment of Intensive Care Medicine, Yunfu People's Hospital, Yunfu 527300, China.
Baoshan HuoDepartment of Intensive Care Medicine, Foshan Second People's Hospital, Foshan 528000, China.
Hanqi LaiDepartment of Intensive Care Medicine, Puning Overseas Chinese Hospital, Puning 515300, China.
Yang LiDepartment of Intensive Care Medicine, Affiliated Tumor Hospital of Guangxi Medical University, Nanning 530021, China.
Bin LiuDepartment of Intensive Care Medicine, Zhujiang Hospital, Southern Medical University, Guangzhou 510282, China.
Huojin DengDepartment of Intensive Care Medicine, Zhujiang Hospital, Southern Medical University, Guangzhou 510282, China.
Qianwen WangDepartment of Intensive Care Medicine, Zhujiang Hospital, Southern Medical University, Guangzhou 510282, China.
Dujuan LiDepartment of Intensive Care Medicine, Zhujiang Hospital, Southern Medical University, Guangzhou 510282, China.
Ping ChangDepartment of Intensive Care Medicine, Zhujiang Hospital, Southern Medical University, Guangzhou 510282, China.
Sha LiDepartment of Intensive Care Medicine, Fifth Affiliated Hospital of Southern Medical University, Guangzhou 510900, China.
Hua WangDepartment of Intensive Care Medicine, Zhujiang Hospital, Southern Medical University, Guangzhou 510282, China.
Zhujiang Hospital · CNFoshan Second People's Hospital · CNPunan Hospital · CNSouthern Medical University · CNThird Affiliated Hospital of Southern Medical University · CNTumor Hospital of Guangxi Medical University · CNYuncheng University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo investigate the therapeutic effect and safety of early physical therapy for acute gastrointestinal injury (AGI) in septic patients receiving mechanical ventilation.

methodsA randomized controlled trial was conducted in the ICU of a tertiary teaching hospital from May, 2017 to March, 2018. The patients diagnosed with sepsis complicated by AGI during mechanical ventilation were recruited and block-randomized into intervention group and control group. Both groups received standard therapy of sepsis, and the patients in the intervention group also received physical therapy as soon as they were hemodynamically stable. The outcome measures included the recovery of AGI, ICU mortality, duration and outcomes of mechanical ventilation and the length of ICU stay.

resultsA total of 60 patients were initially included, and 34 of them completed the study, including 16 in the intervention group and 18 in the control group. After physical rehabilitation, the number of patients with a cure of AGI did not significantly differ between the two group (

conclusionsEarly rehabilitation therapy does not reduce the incidence of AGI but can lower AGI scores and alleviate gastrointestinal symptoms in patients with sepsis during mechanical ventilation. The results still await further verification by welldesigned multicenter clinical trials with large sample sizes.

Indexed as

Respiration, ArtificialSepsisHumansIncidenceIntensive Care UnitsLength of StayPhysical Therapy ModalitiesPilot Projectsacute gastrointestinal injurymechanical ventilationphysical therapysepsis

Identifiers

PMID31852650
PMCPMC6926083
OpenAlexW2997920170

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.