Evidence map›Paper›PMID 31852640›Full record

ArticleNan fang yi ke da xue xue bao = Journal of Southern Medical University2019

[Exogenous hydrogen sulfide improves erectile dysfunction by inhibiting apoptosis of corpus cavernosum smooth muscle cells in rats with cavernous nerve injury].

Qinyu Zeng, Shuhua He, Liren Zhong, Li Wang, Fengzhi Cheng, Haibo Zhang, Jialiang Hui, Anyang Wei

Abstract read
In one paragraph

Article in Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Qinyu ZengDepartment of Urology, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.
Shuhua HeDepartment of Urology, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.
Liren ZhongDepartment of Urology, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.
Li WangDepartment of Urology, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.
Fengzhi ChengDepartment of Urology, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.
Haibo ZhangDepartment of Urology, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.
Jialiang HuiDepartment of Urology, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.
Anyang WeiDepartment of Urology, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.
Nanfang Hospital · CNSouthern Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo explore the effects of exogenous hydrogen sulfide (H2S) on apoptosis of corpus cavernosum smooth muscle cells (CCSMCs) and erectile dysfunction (ED) in rats with bilateral cavernous nerve injury (BCNI).

methodsTwentyfour male SD rats were randomly divided into 3 groups (

resultsAfter 4 weeks of treatment, the rats in BCNI+NaHS group showed a significantly higher ICP/MAP ratio than those in BCNI group (

conclusionsExogenous H2S enhance the expression of the classic apoptotic protein Bcl-2 and reduces apoptosis of CCSMC to improve the erectile function in rats with BCNI.

Indexed as

Erectile DysfunctionAnimalsApoptosisDisease Models, AnimalHumansHydrogen SulfideMaleMyocytes, Smooth MusclePenile ErectionPenisRatsRats, Sprague-DawleyHydrogen Sulfideapoptosisbilateral cavernous nerve injurycorpus cavernosum smooth muscle cellserectile dysfunctionhydrogen sulfide

Identifiers

PMID31852640
PMCPMC6926078
OpenAlexW3005131678

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.