Evidence map›Paper›PMID 31852533›Full record

ArticleBMC pharmacology & toxicology2019

Simultaneous exposure to vinylcyclohexene and methylmercury in Drosophila melanogaster: biochemical and molecular analyses.

Bruna Candia Piccoli, Ana Lúcia Anversa Segatto, Cláudia Sirlene Oliveira, Fernanda D'Avila da Silva, Michael Aschner, João Batista Teixeira da Rocha

Open access · goldAbstract read
In one paragraph

Article in BMC pharmacology & toxicology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 18 citations in OpenAlex.

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  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Bruna Candia PiccoliDepartamento de Bioquímica e Biologia Molecular, Centro de Ciências Naturais e Exatas, Universidade Federal de Santa Maria, Santa Maria, RS, Brazil.
Ana Lúcia Anversa SegattoDepartamento de Bioquímica e Biologia Molecular, Centro de Ciências Naturais e Exatas, Universidade Federal de Santa Maria, Santa Maria, RS, Brazil.
Cláudia Sirlene OliveiraDepartamento de Bioquímica e Biologia Molecular, Centro de Ciências Naturais e Exatas, Universidade Federal de Santa Maria, Santa Maria, RS, Brazil.
Fernanda D'Avila da SilvaDepartamento de Bioquímica e Biologia Molecular, Centro de Ciências Naturais e Exatas, Universidade Federal de Santa Maria, Santa Maria, RS, Brazil.
Michael AschnerDepartment of Molecular Pharmacology, Albert Einstein College of Medicine, Bronx, NY, USA.
João Batista Teixeira da RochaDepartamento de Bioquímica e Biologia Molecular, Centro de Ciências Naturais e Exatas, Universidade Federal de Santa Maria, Santa Maria, RS, Brazil. jbtrocha@yahoo.com.br.
Universidade Federal de Santa Maria · BRAlbert Einstein College of Medicine · USInstituto de Tecnologia do Paraná · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundExposure to vinylcyclohexene (VCH) and methylmercury (MeHg

methodsReactive species production, glutathione S-transferase (GST) and acetylcholinesterase (AChE) activities were evaluated after exposure and co-exposure to VCH (1 mM) and MeHg

resultsSurvival decreased only in flies co-exposed to VCH and MeHg

conclusionThe results suggest that exposure to VCH and MeHg

Indexed as

AcetylcholinesteraseAnimalsCyclohexenesDose-Response Relationship, DrugDrosophila melanogasterDrosophila ProteinsDrug SynergismGene ExpressionGlutathione TransferaseMethylmercury CompoundsOxidative Stress4-vinylcyclohexeneAcetylcholinesteraseCyclohexenesDrosophila ProteinsGlutathione Transferasemethylmercuric chlorideMethylmercury CompoundsAlternative modelDrosophila melanogasterInflammatory responseOxidative stressXenobiotic

Identifiers

PMID31852533
PMCPMC6921456
OpenAlexW2994622754

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.