ArticleTrials2019
Ethics of alternative trial designs and methods in low-resource settings.
Article in Trials, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed.
- Ethical considerations in implementation research: a scoping review of key principles, unintended consequences, and emerging ethical guidance.Implementation science communications · 2025Review
- How community members in Uganda perceive controlled human infection studies.Research ethics · 2025Article
- No frugal innovation without frugal evaluation: the Global IDEAL Sub-Framework.BMJ surgery, interventions, & health technologies · 2024Article
- Stakeholders' experiences of ethical challenges in cluster randomized trials in a limited resource setting: a qualitative analysis.Research ethics · 2024Article
- Empowering local research ethics review of antibacterial mass administration research.Infectious diseases of poverty · 2022Review
- Ethics and regulatory complexities posed by a pragmatic clinical trial: a case study from Lilongwe, Malawi.Malawi medical journal : the journal of Medical Association of Malawi · 2022Article
- Maximising impactful, locally relevant global mental health research conducted in low and middle income country settings: ethical considerations.Wellcome open research · 2022Article
- A situation analysis of competences of research ethics committee members regarding review of research protocols with complex and emerging study designs in Uganda.BMC medical ethics · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
This editorial introduces articles in this Special Issue, which are based on presentations given at the 2017 meeting of the Global Forum of Bioethics in Research meeting. The main themes presented at the meeting were the use of cluster randomized trials, stepped-wedge cluster randomized trials, and controlled human infection models in research conducted in low-resource settings. The editorial sets out which ethical issues may arise in the context of alternative trial designs and describes the articles in this issue that addresses some or more of the ethical issues, such as justification of the research design, risk-benefit evaluations and consent.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.