Evidence map›Paper›PMID 31852497›Full record

ArticleRadiation oncology (London, England)2019

Intrafractional 6D head movement increases with time of mask fixation during stereotactic intracranial RT-sessions.

Julian Mangesius, Thomas Seppi, Rocco Weigel, Christoph Reinhold Arnold, Danijela Vasiljevic, Georg Goebel, Peter Lukas, Ute Ganswindt, Meinhard Nevinny-Stickel

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Radiation oncology (London, England), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03896555 (Intrafractional 6D Head Movement With Mask Fixation During Stereotactic Intracranial RT-sessions), which is not on this map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
4.2field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03896555 completednot on this map

Intrafractional 6D Head Movement With Mask Fixation During Stereotactic Intracranial RT-sessions

TypeobservationalSponsorMedical University InnsbruckRan2014 to 2015Enrolled5ConditionsBrain Metastases, AdultArmsExacTrac position verification
3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.

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  18. Performance assessment of two motion management systems for frameless stereotactic radiosurgery.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Julian MangesiusDepartment of Therapeutic Radiology and Oncology, Medical University of Innsbruck, Anichstraße 35, A-6020, Innsbruck, Austria.
Thomas SeppiDepartment of Therapeutic Radiology and Oncology, Medical University of Innsbruck, Anichstraße 35, A-6020, Innsbruck, Austria.
Rocco WeigelDepartment of Therapeutic Radiology and Oncology, Medical University of Innsbruck, Anichstraße 35, A-6020, Innsbruck, Austria.
Christoph Reinhold ArnoldDepartment of Therapeutic Radiology and Oncology, Medical University of Innsbruck, Anichstraße 35, A-6020, Innsbruck, Austria.
Danijela VasiljevicDepartment of Therapeutic Radiology and Oncology, Medical University of Innsbruck, Anichstraße 35, A-6020, Innsbruck, Austria. Danijela.Vasiljevic@i-med.ac.at.
Georg GoebelDepartment of Medical Statistics, Informatics and Health Economics, Medical University of Innsbruck, Innsbruck, Austria.
Peter LukasDepartment of Therapeutic Radiology and Oncology, Medical University of Innsbruck, Anichstraße 35, A-6020, Innsbruck, Austria.
Ute GanswindtDepartment of Therapeutic Radiology and Oncology, Medical University of Innsbruck, Anichstraße 35, A-6020, Innsbruck, Austria.
Meinhard Nevinny-StickelDepartment of Therapeutic Radiology and Oncology, Medical University of Innsbruck, Anichstraße 35, A-6020, Innsbruck, Austria.
Innsbruck Medical University · ATUniversität Innsbruck · AT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe present study investigates the intrafractional accuracy of a frameless thermoplastic mask used for head immobilization during stereotactic radiotherapy. Non-invasive masks cannot completely prohibit head movements. Previous studies attempted to estimate the magnitude of intrafractional inaccuracy by means of pre- and postfractional measurements only. However, this might not be sufficient to accurately map also intrafractional head movements. MATERIALS AND

methodsIntrafractional deviation of mask-fixed head positions was measured in five patients during a total of 94 fractions by means of close-meshed repeated ExacTrac measurements (every 1.4 min) conducted during the entire treatment session. A median of six (range: 4 to 11) measurements were recorded per fraction, delivering a dataset of 453 measurements.

resultsRandom errors (SD) for the x, y and z axes were 0.27 mm, 0.29 mm and 0.29 mm, respectively. Median 3D deviation was 0.29 mm. Of all 3D intrafractional motions, 5.5 and 0.4% exceeded 1 mm and 2 mm, respectively. A moderate correlation between treatment duration and mean 3D displacement was determined (r

conclusionPre- and post-treatment measurement is not sufficient to adequately determine the range of intrafractional head motion. Thermoplastic masks provide both reliable interfractional and intrafractional immobilization for image-guided stereotactic hypofractionated radiotherapy. Greater positioning accuracy may be obtained by reducing treatment duration (< 6 min) and applying intrafractional correction.

trial registrationClinicaltrials.gov, NCT03896555, Registered 01 April 2019 - retrospectively registered.

Indexed as

Head MovementsPhantoms, ImagingHead and Neck NeoplasmsHumansImage Processing, Computer-AssistedImmobilizationMasksMovementOrgans at RiskPatient PositioningRadiosurgeryRadiotherapy DosageRadiotherapy, Intensity-ModulatedRadiotherapy Planning, Computer-AssistedTomography, X-Ray ComputedExacTracFrameless stereotactic radiation therapyIntrafractional accuracyThermoplastic mask head fixationX-ray position monitoring

Identifiers

PMID31852497
PMCPMC6921566
OpenAlexW2995372320

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.