Evidence map›Paper›PMID 31852296›Full record

SynthesisThe Journal of international medical research2020

The CD14 gene -159C/T polymorphism and the risk of ischemic stroke: a meta-analysis.

Meihua Xu, Linghua Wang, Lihua Sun, Zhaodong Li, Hua Zhang

Abstract readMeta-Analysis
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in The Journal of international medical research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Meihua XuDepartment of Neurology, Hangzhou Red Cross Hospital, Hangzhou, China.
Linghua WangNursing Department, Hangzhou Red Cross Hospital, Hangzhou, China.
Lihua SunDepartment of Neurology, Hangzhou Red Cross Hospital, Hangzhou, China.
Zhaodong LiClinical Laboratory, Hangzhou Red Cross Hospital, Hangzhou, China.
Hua ZhangDepartment of Neurology, Hangzhou Red Cross Hospital, Hangzhou, China.ORCID https://orcid.org/0000-0002-8910-3481

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo investigate the association between the

methodsRelevant literature was searched by retrieving EMBASE, Web of Science, Chinese National Knowledge Infrastructure, and PubMed databases. R version 3.33 software was applied to calculate pooled odds ratios (ORs) and 95% confidence intervals (CIs).

resultsSeven qualified studies with a total of 2058 IS patients and 2123 controls were included. There was no significant association between the

conclusionOur findings suggest that the

Indexed as

Brain IschemiaIschemic StrokeLipopolysaccharide ReceptorsGenetic Predisposition to DiseaseHumansPolymorphism, Single NucleotideLipopolysaccharide ReceptorsatherogenesisCD14Hardy–Weinberg equilibriumischemic strokemeta-analysispolymorphism

Identifiers

PMID31852296
PMCPMC7607219

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.