ArticleThe Journal of international medical research2020
Assessment of plasma homocysteine levels in patients with craniocerebral injury and prognosis.
Article in The Journal of international medical research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Elevation of C-reactive protein and homocysteine levels as reliable biomarkers for assessing injury severity and prognosis in traumatic brain injury.Scientific reports · 2025Article
- Relationship between Prognosis with Dynamic Changes of Thyroid Hormone and Cortisol Hormone in Patients with Severe Craniocerebral Injury.Evidence-based complementary and alternative medicine : eCAM · 2022Article
- Treatment effects of monosialotetrahexosylganglioside on severe traumatic brain injury in adults.American journal of translational research · 2022Article
- Change of Levels of NGF, ACTH, and AVP in the Cerebrospinal Fluid after Decompressive Craniectomy of Craniocerebral Injury and Their Relationship with Communicating Hydrocephalus.Evidence-based complementary and alternative medicine : eCAM · 2021Article
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo investigate the effect of plasma homocysteine (Hcy) and C-reactive protein (CRP) levels in patients with craniocerebral injury.
methodsA retrospective analysis of data from patients with craniocerebral injury who underwent surgery. Patients were stratified according to the extent of the craniocerebral injury into severe, moderate and mild craniocerebral injury groups. Serum Hcy and CRP levels were determined at admission, at 7 days after treatment and at 3 months after injury. Univariate and multivariate Cox regression analyses were undertaken to identify prognostic factors.
resultsThe study enrolled 96 patients: 29 patients with mild injury; 33 patients with moderate injury; and 34 patients with severe injury. Serum Hcy and CRP levels at admission were significantly higher in the severe craniocerebral injury group than in the other two groups; and they were significantly higher the moderate craniocerebral injury group compared with the mild craniocerebral injury group. Serum Hcy and CRP levels of the three groups of patients were significantly lower after 7 days of treatment than those before treatment. The levels of Hcy and CRP were positively correlated in all three groups.
conclusionSerum Hcy and CRP levels in patients could be used to monitor the condition and prognosis of patients with craniocerebral injury.
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