Evidence map›Paper›PMID 31852087›Full record

Observational studyMedicine2019

Carotid artery blood flow velocities during open-heart surgery and its association with delirium: A prospective, observational pilot study.

Martin H Bernardi, Martin Wahrmann, Martin Dworschak, Clemens Kietaibl, Robin Ristl, Maximilian Edlinger-Stanger, Andrea Lassnigg, Michael J Hiesmayr, Ulrike Weber

Open access · goldAbstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in Medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Observational
  2. Article
  3. Article
  4. The Rheology of the Carotid Sinus: A Path Toward Bioinspired Intervention.Frontiers in bioengineering and biotechnology · 2021
    Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Martin H BernardiDivision of Cardiac Thoracic Vascular Anesthesia and Intensive Care Medicine, Medical University of Vienna.
Martin WahrmannDivision of Cardiac Thoracic Vascular Anesthesia and Intensive Care Medicine, Medical University of Vienna.
Martin DworschakDivision of Cardiac Thoracic Vascular Anesthesia and Intensive Care Medicine, Medical University of Vienna.
Clemens KietaiblDepartment of Anesthesia, Intensive Care Medicine and Pain Medicine, Medical University of Vienna, Waehringer Guertel 18-20.
Robin RistlCenter for Medical Statistics, Informatics and Intelligent Systems, Medical University of Vienna, Spitalgasse 23, A-1090 Vienna, Austria.
Maximilian Edlinger-StangerDivision of Cardiac Thoracic Vascular Anesthesia and Intensive Care Medicine, Medical University of Vienna.
Andrea LassniggDivision of Cardiac Thoracic Vascular Anesthesia and Intensive Care Medicine, Medical University of Vienna.
Michael J HiesmayrDivision of Cardiac Thoracic Vascular Anesthesia and Intensive Care Medicine, Medical University of Vienna.
Ulrike WeberDivision of Cardiac Thoracic Vascular Anesthesia and Intensive Care Medicine, Medical University of Vienna.
Medical University of Vienna · AT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this prospective observational single-centre pilot study was to evaluate the association between alterations in carotid artery blood flow velocities during cardiac surgery and postoperative delirium.Carotid artery blood flow velocity was determined perioperatively at 5 different timepoints by duplex sonography in 36 adult cardiac surgical patients. Delirium was assessed using the Confusion Assessment Method for the ICU and the Intensive Care Delirium Screening Checklist. Additionally, blood flow velocities in the middle cerebral arteries, differences in regional cerebral tissue oxygenation and quantity and quality of microemboli were measured.Delirium was detected in 7 of 36 patients. After cardiopulmonary bypass carotid artery blood flow velocities increased by +23 cm/second (95% confidence interval (CI) 9-36 cm/second) in non-delirious patients compared to preoperative values (P = .002), but not in delirious patients (+3 cm/second [95% CI -25 to 32 cm/second], P = .5781). Middle cerebral artery blood flow velocities were higher at aortic de-cannulation in non-delirious patients (29 cm/second [inter-quartile range (IQR), 24-36 cm/second] vs 12 cm/second [IQR, 10-19 cm/second]; P = .017). Furthermore, brain tissue oxygenation was higher in non-delirious patients during surgery.Our results suggest that higher cerebral blood flow velocities after aortic de-clamping and probably also improved brain oxygenation might be beneficial to prevent postoperative delirium.

Indexed as

AgedBlood Flow VelocityCardiac Surgical ProceduresCarotid Artery, CommonDeliriumFemaleFollow-Up StudiesHumansIntraoperative PeriodMaleMiddle AgedPilot ProjectsPostoperative ComplicationsPredictive Value of TestsProspective StudiesUltrasonography, Doppler, Duplex

Identifiers

PMID31852087
PMCPMC6922412
OpenAlexW2996512751

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.