ArticleClinical cardiology2020
Prognostic value of elevated cardiac troponin I in patients with intracerebral hemorrhage.
Article in Clinical cardiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.
- Elevated troponin levels as a predictor of mortality in patients with acute stroke: a systematic review and meta-analysis.Frontiers in neurology · 2024Pooled it
- Acute Myocardial Injury in Spontaneous Intracerebral Hemorrhage: A Secondary Observational Analysis of the FAST Trial.Journal of the American Heart Association · 2024Trial
- Methylated PIH1D1 as a Heart-Specific Biomarker for Anthracycline-Induced Cardiac Remodeling in Breast Cancer Patients.JACC. Basic to translational science · 2026Article
- Association between admission high-sensitivity cardiac troponin T levels and clinical outcomes in acute intracerebral hemorrhage: a prospective cohort study.BMC neurology · 2026Article
- Predicting Blood Pressure and Blood Pressure Variability in Spontaneous Intracerebral Hemorrhage in the Emergency Department Using Machine Learning.Journal of clinical medicine · 2025Article
- Prognostic Significance of High-Sensitivity Troponin-T and Hematological Biomarkers in Spontaneous Intracranial Hemorrhage Patients Undergoing Surgery.Diagnostics (Basel, Switzerland) · 2025Article
- Predictors and Implications of Myocardial Injury in Intracerebral Hemorrhage.Clinical neuroradiology · 2025Article
- Impact of Acute Myocardial Injury on Short- and Long-Term Outcomes in Patients With Primary Intracerebral Hemorrhage.Journal of the American Heart Association · 2025Article
- Myocardial injury in spontaneous intracerebral hemorrhage is not predicted by prior cardiac disease or neurological status: results from the Mannheim Stroke database.Frontiers in neurology · 2025Article
- Prognostic relationship between high sensitivity troponin I level, hematoma volume and glasgow coma score in patients diagnosed with spontaneous intracerebral hemorrhage.Irish journal of medical science · 2024Observational
- Clinical Interpretation of Serum Troponin in the Era of High-Sensitivity Testing.Diagnostics (Basel, Switzerland) · 2024Review
- Long-term prognostic value of high-sensitivity cardiac troponin-I in patients with idiopathic dilated cardiomyopathy.Open medicine (Warsaw, Poland) · 2023Article
- Emergency department point-of-care biomarkers and day 90 functional outcome in spontaneous intracerebral hemorrhage: A single-center pilot study.Experimental and therapeutic medicine · 2022Article
- High-Sensitivity Troponin: A Review on Characteristics, Assessment, and Clinical Implications.Disease markers · 2022Review
- The relationship of α-hydroxybutyrate dehydrogenase with 1-year outcomes in patients with intracerebral hemorrhage: A retrospective study.Frontiers in neurology · 2022Article
- Changes of Electrocardiogram and Myocardial Enzymes in Patients with Intracerebral Hemorrhage.Disease markers · 2022Article
- Prognostic value of elevated cardiac troponin I in patients with intracerebral hemorrhage.Clinical cardiology · 2020Article
- Admission Emergency Department Point-of-care Biomarkers for Prediction of Early Mortality in Spontaneous Intracerebral Hemorrhage.In vivo (Athens, Greece)Article
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
backgroundAlthough cardiac troponin has been well established as diagnostic and prognostic makers for acute coronary heart disease, the prognostic value of elevated cardiac troponin in patients with intracerebral hemorrhage (ICH) was inconsistent and not systematically evaluated. HYPOTHESIS: We proposed the hypothesis that the practical utility of cardiac troponin levels for prediction of mortality and poor outcome in ICH patients.
methodsA total of 1004 patients with ICH were retrospectively reviewed and qualified for further analysis from June 2012 to December 2015. The patients were divided into different groups based on measurements of cardiac troponin I (cTnI) at the time of admission and the following day. Multivariate Cox proportional hazards analysis were performed to determine the independent prognostic value of the cTnI for patients in-hospital mortality and poor outcomes, the receiver operator characteristic (ROC) analysis was performed to assess the predictive value of cTnI, ICH score, and combination of them.
resultsSerum cTnI level was an independent predictor in-hospital mortality (positive vs negative, HR (hazard ratios) = 3.44, 95% CI (confidence interval) 1.66-7.13, P < .001) and poor outcomes in patients with ICH (positive vs negative, HR = 6.69, 95% CI 4.25-10.52, P < .001). Addition of cTnI to ICH score significantly improved the prognostic discrimination for both in-hospital mortality and poor outcomes.
conclusionSerum cTnI levels may be valuable as predictor for in hospital mortality and poor outcomes and may be useful in the risk stratification of ICH during hospitalization.
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