Evidence map›Paper›PMID 31851531›Full record

ArticleJournal of enzyme inhibition and medicinal chemistry2020

Synthesis, antibacterial and anticancer activity, and docking study of aminoguanidines containing an alkynyl moiety.

Xianqing Deng, Mingxia Song

Abstract read
In one paragraph

Article in Journal of enzyme inhibition and medicinal chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. A novel bakuchiol aminoguanidine derivative induces apoptosis in human triple-negative breast cancer cells.Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences · 2024
    Article
  6. Article
  7. Article
  8. RSC advances · 2022
    Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Xianqing DengBasic Medical and Pharmacy College, Jinggangshan University, Ji'an, China.
Mingxia SongBasic Medical and Pharmacy College, Jinggangshan University, Ji'an, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Two series of aminoguanidines containing an alkynyl moiety were designed, synthesised, and screened for antibacterial and anticancer activities. Generally, the series

Indexed as

A549 CellsAnti-Bacterial AgentsAntineoplastic AgentsCell LineCell ProliferationDose-Response Relationship, DrugDrug Screening Assays, AntitumorEscherichia coliGuanidinesHumansMicrobial Sensitivity TestsModels, MolecularMolecular StructureStaphylococcus aureusStructure-Activity RelationshipAnti-Bacterial AgentsAntineoplastic AgentsGuanidinespimagedineAlkynylaminoguanidineantibacterial activityanticancerdocking

Identifiers

PMID31851531
PMCPMC6968633

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.