ArticleACS nano2020
Multimodal Multiplexed Immunoimaging with Nanostars to Detect Multiple Immunomarkers and Monitor Response to Immunotherapies.
Erratum issuedOpen access · greenAbstract read
In one paragraph
Article in ACS nano, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 35 papers.
0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
2.8field-weighted citation impact, top 8% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
35 citing papers in PubMed, 63 citations in OpenAlex.
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- Gold Polymer Nanomaterials: A Promising Approach for Enhanced Biomolecular Imaging.Nanotheranostics · 2024Review
- Monitoring Metabolic Changes in Response to Chemotherapies in Cancer with Raman Spectroscopy and Metabolomics.Analytical chemistry · 2023Article
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- First Trimester Prediction of Preterm Birth in Patient Plasma with Machine-Learning-Guided Raman Spectroscopy and Metabolomics.ACS applied materials & interfaces · 2023Article
- The Emerging Role of Raman Spectroscopy as an Omics Approach for Metabolic Profiling and Biomarker Detection toward Precision Medicine.Chemical reviews · 2023Review
- Physicochemical Properties and Route of Systemic Delivery Control the In Vivo Dynamics and Breakdown of Radiolabeled Gold Nanostars.Small (Weinheim an der Bergstrasse, Germany) · 2023Article
- Artificial intelligence and digital biomarker in precision pathology guiding immune therapy selection and precision oncology.Cancer reports (Hoboken, N.J.) · 2023Review
- Combining Acoustic Bioprinting with AI-Assisted Raman Spectroscopy for High-Throughput Identification of Bacteria in Blood.Nano letters · 2023Article
- Highly Excretable Gold Supraclusters for TranslatableACS nano · 2023Article
- Solution-Based Ultra-Sensitive Surface-Enhanced Raman Scattering Detection of the Toxin Bacterial Biomarker Pyocyanin in Biological Fluids Using Sharp-Branched Gold Nanostars.Analytical chemistry · 2023Article
- Nanotheranostic Strategies for Cancer Immunotherapy.Small methods · 2022Review
Corrections and comments
- Erratum issued
Authors and funding
17 authors at 3 institutions in 2 countries.
Yu-Chuan OuDepartment of Chemical and Biomolecular Engineering , Vanderbilt University , Nashville , Tennessee 37235 , United States.
Xiaona WenDepartment of Chemical and Biomolecular Engineering , Vanderbilt University , Nashville , Tennessee 37235 , United States.
Christopher A JohnsonDepartment of Veterans Affairs , Tennessee Valley Healthcare System , Nashville , Tennessee 37212 , United States.
Daniel ShaeDepartment of Chemical and Biomolecular Engineering , Vanderbilt University , Nashville , Tennessee 37235 , United States.
Oscar D AyalaDepartment of Biomedical Engineering , Vanderbilt University , Nashville , Tennessee 37235 , United States.
Joseph A WebbDepartment of Chemical and Biomolecular Engineering , Vanderbilt University , Nashville , Tennessee 37235 , United States.
Eugene C LinRadiology and Radiological Sciences , Vanderbilt University School of Medicine , Nashville , Tennessee 37232 , United States.
Rossane C DeLappCivil and Environmental Engineering , Vanderbilt University , Nashville , Tennessee 37235 , United States.
Kelli L BoydDepartment of Pathology, Microbiology and Immunology , Vanderbilt University School of Medicine , Nashville , Tennessee 37232 , United States.
Ann RichmondDepartment of Veterans Affairs , Tennessee Valley Healthcare System , Nashville , Tennessee 37212 , United States.
Anita Mahadevan-JansenDepartment of Biomedical Engineering , Vanderbilt University , Nashville , Tennessee 37235 , United States.
Marjan RafatDepartment of Chemical and Biomolecular Engineering , Vanderbilt University , Nashville , Tennessee 37235 , United States.
John T WilsonDepartment of Chemical and Biomolecular Engineering , Vanderbilt University , Nashville , Tennessee 37235 , United States.ORCID 0000-0002-9144-2634
Justin M BalkoVanderbilt Center for Immunobiology , Vanderbilt University School of Medicine , Nashville , Tennessee 37232 , United States.
Mohammed N TantawyRadiology and Radiological Sciences , Vanderbilt University School of Medicine , Nashville , Tennessee 37232 , United States.
Anna E VilgelmDepartment of Veterans Affairs , Tennessee Valley Healthcare System , Nashville , Tennessee 37212 , United States.
Rizia BardhanDepartment of Chemical and Biomolecular Engineering , Vanderbilt University , Nashville , Tennessee 37235 , United States.ORCID 0000-0002-5854-652X
Vanderbilt University · USIowa State University · USNational Chung Cheng University · TW
Funding
Tumor Immunology and Microenvironment Research ProgramP30CA068485 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI MATTHEW J TYSKA · 1995 to 2026
$172.8MTISSUE CoreP50CA098131 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI PARK, BEN HO, PIETENPOL, JENNIFER A · 2003 to 2024
$48.7MTranslational Analysis CoreP30DK058404 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI RICHARD M. PEEK · 2002 to 2026
$29.9MVanderbilt Diabetes Research CenterP30DK020593 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI OWEN P MCGUINNESS · 2012 to 2026
$29.3MShop Module CoreP30EY008126 · NEI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Kevin L Schey · 1989 to 2026
$19.6MVanderbilt Mouse Metabolic Physiology CenterU24DK059637 · NIDDK · VANDERBILT UNIVERSITY · PI WASSERMAN, DAVID H · 2001 to 2015
$14.9MPostdoctoral Training in Biomedical MRI and MRST32EB001628 · NIBIB · VANDERBILT UNIVERSITY MEDICAL CENTER · PI John C Gore · 2003 to 2026
$7.0MTargeting the NF-kappaB Pathway in MelanomaR01CA116021 · NCI · VANDERBILT UNIVERSITY · PI RICHMOND, ANN, YAN, CHI · 2005 to 2024
$6.7MCombining senescence-inducing and senolytic agents to improve melanoma therapyR37CA233770 · NCI · VANDERBILT UNIVERSITY · PI VILGELM, ANNA E · 2019 to 2025
$2.4MOptimizing Response to Immune Checkpoint Inhibitor Therapy for Breast Cancer: A Role for Inhibitors of the PI3K pathwayR01CA243326 · NCI · VANDERBILT UNIVERSITY · PI RICHMOND, ANN, YAN, CHI · 2020 to 2024
$1.8MDeconstructing the Tumor Microenvironment and its Role in MetastasisR00CA201304 · NCI · VANDERBILT UNIVERSITY · PI RAFAT, MARJAN · 2018 to 2020
$728kBLR&D Merit Review Research Career Scientist (RCS) Award (IK6)IK6BX005225 · VA · VETERANS HEALTH ADMINISTRATION · PI RICHMOND, ANN · 2020 to 2023
–BLRD VA I01 BX002301BLRD VA IK6 BX005225NCI NIH HHS P30 CA068485NCI NIH HHS P50 CA098131NCI NIH HHS R00 CA201304NCI NIH HHS R01 CA116021NCI NIH HHS R01 CA243326NCI NIH HHS R37 CA233770NEI NIH HHS P30 EY008126NIBIB NIH HHS T32 EB001628NIDDK NIH HHS P30 DK020593NIDDK NIH HHS P30 DK058404NIDDK NIH HHS U24 DK059637
Abstract
The overexpression of immunomarker programmed cell death protein 1 (PD-1) and engagement of PD-1 to its ligand, PD-L1, are involved in the functional impairment of cluster of differentiation 8
Indexed as
ImmunotherapyOptical ImagingAnimalsB7-H1 AntigenBiomarkers, TumorCell Line, TumorDisease Models, AnimalGoldMelanomaMetal NanoparticlesMiceParticle SizeSurface PropertiesTumor Necrosis Factor Receptor Superfamily, Member 9B7-H1 AntigenBiomarkers, TumorCd274 protein, mouseGoldTumor Necrosis Factor Receptor Superfamily, Member 9CD8gold nanostarimmunoimagingimmunoPETmultiplexed detectionprogrammed cell death ligand 1Raman spectroscopy
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