Evidence map›Paper›PMID 31851125›Full record

ArticlePharmacogenetics and genomics2020

PharmGKB summary: sertraline pathway, pharmacokinetics.

Rachel Huddart, J Kevin Hicks, Laura B Ramsey, Jeffrey R Strawn, D Max Smith, Margarita Bobonis Babilonia, Russ B Altman, Teri E Klein

Abstract read
In one paragraph

Article in Pharmacogenetics and genomics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Observational
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  10. Article
  11. New Personalized Medicine Model for Medication Management.Journal of personalized medicine · 2026
    Review
  12. Observational
  13. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Rachel HuddartDepartment of Biomedical Data Sciences, Stanford University, Stanford, California.
J Kevin HicksDepartment of Individualized Cancer Management, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida.
Laura B RamseyDepartment of Pediatrics, University of Cincinnati College of Medicine and Cincinnati Children's Hospital Medical Center.
Jeffrey R StrawnDepartment of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, Ohio.
D Max SmithMedStar Health, Columbia, Maryland.
Margarita Bobonis BabiloniaDepartment of Supportive Cancer Medicine, Behavioral Medicine Section, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida.
Russ B AltmanDepartment of Biomedical Data Sciences, Stanford University, Stanford, California.
Teri E KleinDepartment of Biomedical Data Sciences, Stanford University, Stanford, California.

Funding

PharmGKB: pharmacogenomics knowledge for precision medicineR24GM061374 · NIGMS · STANFORD UNIVERSITY · PI ALTMAN, RUSS BIAGIO, KLEIN, TERI ELLEN · 2010 to 2018
$25.2M
THE STANFORD PHARMACOGENETICS KNOWLEDGE BASEU01GM061374 · NIGMS · STANFORD UNIVERSITY · PI ALTMAN, RUSS BIAGIO · 2000 to 2009
$24.0M
NIGMS NIH HHS R24 GM061374NIGMS NIH HHS U01 GM061374
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Drug InteractionsHumansMental DisordersPharmacogenomic VariantsSelective Serotonin Reuptake InhibitorsSertralineSignal TransductionSelective Serotonin Reuptake InhibitorsSertraline

Identifiers

PMID31851125
PMCPMC7008964

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.