Evidence map›Paper›PMID 31850213›Full record

ArticleFrontiers in oncology2019

Recurrent Extradural Myxopapillary Ependymoma With Oligometastatic Spread.

Kristen A Batich, Richard F Riedel, John P Kirkpatrick, Betty C Tong, William C Eward, Char Loo Tan, Patricia D Pittman, Roger E McLendon, Katherine B Peters

Open access · goldAbstract readCase Reports
In one paragraph

Article in Frontiers in oncology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.1field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 16 citations in OpenAlex.

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  8. Clinical management and prognosis of spinal myxopapillary ependymoma: a single-institution cohort of 72 patients.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Kristen A BatichDepartment of Medicine, Duke University Health System, Durham, NC, United States.
Richard F RiedelDivision of Medical Oncology, Department of Medicine, Duke University Health System, Durham, NC, United States.
John P KirkpatrickThe Preston Robert Tisch Brain Tumor Center, Duke University Health System, Durham, NC, United States.
Betty C TongDuke Cancer Institute, Duke University Health System, Durham, NC, United States.
William C EwardDuke Cancer Institute, Duke University Health System, Durham, NC, United States.
Char Loo TanDepartment of Pathology, Duke University Health System, Durham, NC, United States.
Patricia D PittmanDepartment of Pathology, Duke University Health System, Durham, NC, United States.
Roger E McLendonThe Preston Robert Tisch Brain Tumor Center, Duke University Health System, Durham, NC, United States.
Katherine B PetersThe Preston Robert Tisch Brain Tumor Center, Duke University Health System, Durham, NC, United States.
Duke University Health System · USNational University Health System · SG

Funding

Medical Scientist Training Program Training GrantT32GM145449 · NIGMS · DUKE UNIVERSITY · PI Christopher D Kontos · 2022 to 2026
$6.6M
NIGMS NIH HHS T32 GM145449
6 · The paper itself

Abstract

Myxopapillary ependymomas are a slow-growing, grade I type glial tumor in the lumbosacral region. More rarely, they can present as extradural, subcutaneous sacrococcygeal, or perisacral masses, and it is under these circumstances that they are more likely to spread. Here, we report the presentation of a sacrococcygeal mass in patient that was initially resected confirming extradural myxopapillary ependymoma. At initial resection, multiple small pulmonary nodules were detected. This mass recurred 2 years later at the resection site with an interval increase in the previously imaged pulmonary nodules. Resection of both the post-sacral mass and largest lung metastasis confirmed recurrent myxopapillary ependymoma with oligometastatic spread. Because these tumors are rare, with extradural presentation being even more infrequent, to this date there are no definitive therapeutic guidelines for initial treatment and continued surveillance. For myxopapillary ependymoma, current standard of care is first-line maximal surgical resection with or without postoperative radiotherapy depending on the extent of disease and extent of resection. However, there remains insufficient evidence on the role of radiotherapy to oligometastatic foci in providing any further survival benefit or extending time to recurrence. Thus, prospective studies assessing the role of upfront treatment of oligometastases with local resection and adjuvant radiotherapy are needed for improved understanding of extradural myxopapillary ependymoma.

Indexed as

extraduralglial fibrillary acidic proteinmyxopapillary ependymomaoligometastasespost-sacral

Identifiers

PMID31850213
PMCPMC6892774
OpenAlexW2990723576

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.