Evidence map›Paper›PMID 31850177›Full record

ArticleInternational journal of ophthalmology2019

Computer aided diabetic retinopathy detection based on ophthalmic photography: a systematic review and Meta-analysis.

Hui-Qun Wu, Yan-Xing Shan, Huan Wu, Di-Ru Zhu, Hui-Min Tao, Hua-Gen Wei, Xiao-Yan Shen, Ai-Min Sang, Jian-Cheng Dong

Open access · goldAbstract read
In one paragraph

Article in International journal of ophthalmology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Hui-Qun WuDepartment of Medical Informatics, Medical School of Nantong University, Nantong 226001, Jiangsu Province, China.
Yan-Xing ShanDepartment of Medical Informatics, Medical School of Nantong University, Nantong 226001, Jiangsu Province, China.
Huan WuDepartment of Medical Informatics, Medical School of Nantong University, Nantong 226001, Jiangsu Province, China.
Di-Ru ZhuDepartment of Medical Informatics, Medical School of Nantong University, Nantong 226001, Jiangsu Province, China.
Hui-Min TaoDepartment of Medical Informatics, Medical School of Nantong University, Nantong 226001, Jiangsu Province, China.
Hua-Gen WeiDepartment of Medical Informatics, Medical School of Nantong University, Nantong 226001, Jiangsu Province, China.
Xiao-Yan ShenSchool of Information Science and Technology, Nantong University, Nantong 226001, Jiangsu Province, China.
Ai-Min SangDepartment of Ophthalmology, Affiliated Hospital of Nantong University, Nantong 226001, Jiangsu Province, China.
Jian-Cheng DongDepartment of Medical Informatics, Medical School of Nantong University, Nantong 226001, Jiangsu Province, China.
Nantong University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo ensure the diagnostic value of computer aided techniques in diabetic retinopathy (DR) detection based on ophthalmic photography (OP).

methodsPubMed, EMBASE, Ei village, IEEE Xplore and Cochrane Library database were searched systematically for literatures about computer aided detection (CAD) in DR detection. The methodological quality of included studies was appraised by the Quality Assessment Tool for Diagnostic Accuracy Studies (QUADAS-2). Meta-DiSc was utilized and a random effects model was plotted to summarize data from those included studies. Summary receiver operating characteristic curves were selected to estimate the overall test performance. Subgroup analysis was used to identify the efficiency of CAD in detecting DR, exudates (EXs), microaneurysms (MAs) as well as hemorrhages (HMs), and neovascularizations (NVs). Publication bias was analyzed using STATA.

resultsFourteen articles were finally included in this Meta-analysis after literature review. Pooled sensitivity and specificity were 90% (95%CI, 85%-94%) and 90% (95%CI, 80%-96%) respectively for CAD in DR detection. With regard to CAD in EXs detecting, pooled sensitivity, specificity were 89% (95%CI, 88%-90%) and 99% (95%CI, 99%-99%) respectively. In aspect of MAs and HMs detection, pooled sensitivity and specificity of CAD were 42% (95%CI, 41%-44%) and 93% (95%CI, 93%-93%) respectively. Besides, pooled sensitivity and specificity were 94% (95%CI, 89%-97%) and 87% (95%CI, 83%-90%) respectively for CAD in NVs detection. No potential publication bias was observed.

conclusionCAD demonstrates overall high diagnostic accuracy for detecting DR and pathological lesions based on OP. Further prospective clinical trials are needed to prove such effect.

Indexed as

computer aided detectiondiabetic retinopathyMeta-analysis

Identifiers

PMID31850177
PMCPMC6901900
OpenAlexW2993305583

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.