Evidence map›Paper›PMID 31850114›Full record

ReviewOpen access Macedonian journal of medical sciences2019

Treatment of Psoriasis: Novel Approaches to Topical Delivery.

Uwe Wollina, Michael Tirant, Aleksandra Vojvodic, Torello Lotti

2 registry-linked trialsOpen access · diamondAbstract readReview
In one paragraph

Review in Open access Macedonian journal of medical sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04971239 phase4unknown statusnot on this mapstarted 2021, after this paper: background citation

The Efficacy and Safety of Topical Methotrexate Microemulsion in Combination With Excimer Light and Narrow Band-ultraviolet B in the Treatment of Plaque Psoriasis

TypeinterventionalSponsorAssiut UniversityRan2021 to 2022Enrolled30ConditionsPsoriasis, MethotrexateArmstopical methotrexate micoemulsion, Excimer light, Narrow band ultraviolet B
NCT06203470 phase4not yet recruitingnot on this mapstarted 2024, after this paper: background citation

Efficacy and Safety of Mesobotox as a Potential New Therapeutic Modality of Psoriasis Vulgaris in Comparison/Combination With Topical Calcineurin Inhibitor

TypeinterventionalSponsorAssiut UniversityRan2024 to 2026Enrolled60ConditionsPsoriasis VulgarisArmsBotulinum Toxin-A, Tacrolimus
3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 42 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Anti-psoriatic potential of nanocarrier formulated with Deverra tortuosa DC. and Deverra triradiata hochst aerial extracts: in vivo evaluation in mice.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2026
    Article
  4. Article
  5. Review
  6. Microsponge Drug Delivery Systems: Advancing the Therapeutic Efficacy of Anti-Inflammatory Medications.Anti-inflammatory & anti-allergy agents in medicinal chemistry · 2026
    Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. Review
  12. Article
  13. Review
  14. Article
  15. Article
  16. Review
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  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 3 countries.

Uwe WollinaDepartment of Dermatology and Allergology, Städtisches Klinikum Dresden, Academic Teaching Hospital, Dresden, Germany.
Michael TirantDepartment of Dermatology, University of Rome "G. Marconi", Rome, Italy.
Aleksandra VojvodicMilitary Medical Academy of Belgrade, Belgrade, Serbia.
Torello LottiDepartment of Dermatology, University of Rome "G. Marconi", Rome, Italy.
Marconi University · ITMilitary Medical Academy · RSStädtisches Klinikum Dresden · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Topical treatment is the cornerstone for the management of mild to moderate psoriasis. Despite efforts in drug development, patient's satisfaction with the available topical treatments is limited. A strategy to improve safety, efficacy and comfort of topical treatment provides the development of new drug delivery and drug carrier systems. This review provides an overview of recent advances in this field with a focus on psoriasis. Laser-assisted drug delivery, foam formulations, nanoparticles, ethosomes, and niomes are considered. Hopefully, these new developments will improve topical drug therapy and patient satisfaction.

Indexed as

EthosomesFoamsLaser-assisted drug deliveryNanoparticlesNiosomesPsoriasisTopical drug therapy

Identifiers

PMID31850114
PMCPMC6910788
OpenAlexW2981220799

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.