Evidence map›Paper›PMID 31849924›Full record

ReviewFrontiers in immunology2019

Mucosal Immunity and the FOXO1 Transcription Factors.

Dana T Graves, Tatyana N Milovanova

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 79 papers.

0numbers the graph read from it
0cells of the map it votes in
79citing papers in PubMed
5.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

79 citing papers in PubMed, 137 citations in OpenAlex.

  1. Article
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  6. Research progress on the mechanism of FOXO protein in sepsis.Apoptosis : an international journal on programmed cell death · 2026
    Review
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19 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Dana T GravesDepartment of Periodontics, School of Dental Medicine, University of Pennsylvania, Philadelphia, PA, United States.
Tatyana N MilovanovaDepartment of Periodontics, School of Dental Medicine, University of Pennsylvania, Philadelphia, PA, United States.
University of Pennsylvania · US

Funding

Diabetes-enhanced Experimental PeriodontitisR01DE017732 · NIDCR · UNIV OF MED/DENT OF NJ-NJ DENTAL SCHOOL · PI DANA T GRAVES · 2007 to 2026
$6.5M
Dendritic Cells and Periodontal DiseaseR01DE021921 · NIDCR · UNIVERSITY OF PENNSYLVANIA · PI GRAVES, DANA T · 2012 to 2022
$4.2M
NIDCR NIH HHS R01 DE017732NIDCR NIH HHS R01 DE021921
6 · The paper itself

Abstract

FOXO1 transcription factors affect a number of cell types that are important in the host response. Cell types whose functions are modulated by FOXO1 include keratinocytes in the skin and mucosal dermis, neutrophils and macrophages, dendritic cells, Tregs and B-cells. FOXO1 is activated by bacterial or cytokine stimulation. Its translocation to the nucleus and binding to promoter regions of genes that have

Indexed as

Immunity, MucosalAnimalsDendritic CellsDisease SusceptibilityForkhead Box Protein O1Gene Expression RegulationHumansLymphocytesMacrophagesMonocytesMucous MembranePeriodontal DiseasesSignal TransductionForkhead Box Protein O1bacteriabone lossforkheadgingivaimmunemucosaperiodontal diseaseperiodontitis

Identifiers

PMID31849924
PMCPMC6896163
OpenAlexW2990660417

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.