Evidence map›Paper›PMID 31849851›Full record

ArticleFrontiers in microbiology2019

Intestinal

Dongfang Li, Yinhu Li, Wenkui Dai, Huihui Wang, Chuangzhao Qiu, Su Feng, Qian Zhou, Wenjian Wang, Xin Feng, Kaihu Yao and 7 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in microbiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. [Assessment and management of malnutrition in patients with cirrhosis combined with hepatic encephalopathy].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 6 institutions in 2 countries.

Dongfang LiWuhan National Laboratory for Optoelectronics, Huazhong University of Science and Technology, Wuhan, China.
Yinhu LiDepartment of Computer Science, College of Science and Engineering, City University of Hong Kong, Kowloon Tong, Hong Kong.
Wenkui DaiDepartment of Microbial Research, WeHealthGene Institute, Shenzhen, China.
Huihui WangDepartment of Clinical Nutrition, Shenzhen Children's Hospital, Shenzhen, China.
Chuangzhao QiuDepartment of Microbial Research, WeHealthGene Institute, Shenzhen, China.
Su FengInstitute of Statistics, Nankai University, Tianjin, China.
Qian ZhouDepartment of Computer Science, College of Science and Engineering, City University of Hong Kong, Kowloon Tong, Hong Kong.
Wenjian WangDepartment of Respiratory Diseases, Shenzhen Children's Hospital, Shenzhen, China.
Xin FengDepartment of Microbial Research, WeHealthGene Institute, Shenzhen, China.
Kaihu YaoDepartment of Respiratory Diseases, Beijing Children's Hospital, Beijing, China.
Yanhong LiuDepartment of Microbial Research, WeHealthGene Institute, Shenzhen, China.
Yonghong YangDepartment of Microbial Research, WeHealthGene Institute, Shenzhen, China.
Zhenyu YangDepartment of Microbial Research, WeHealthGene Institute, Shenzhen, China.
Ximing XuInstitute of Statistics, Nankai University, Tianjin, China.
Shuaicheng LiDepartment of Computer Science, College of Science and Engineering, City University of Hong Kong, Kowloon Tong, Hong Kong.
Jurong WeiDepartment of Clinical Nutrition, Shenzhen Children's Hospital, Shenzhen, China.
Ke ZhouWuhan National Laboratory for Optoelectronics, Huazhong University of Science and Technology, Wuhan, China.
Shenzhen Children's Hospital · CNCity University of Hong Kong · HKNankai University · CNBeijing Children’s Hospital · CNHuazhong University of Science and Technology · CNWuhan National Laboratory for Optoelectronics · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Undernutrition (UN) is a worldwide concern affecting morbidity and mortality among children, but the safety and long-term efficacy of its current treatments remain controversial. Recent evidence showing the roles of the gut microbiome (GM) in nutrient absorption indicates its usefulness in alternative interventions to treat UN safely with sustainable amelioration. To enhance our understanding of the GM and childhood undernutrition, we deep sequenced the gut metagenomes of 65 children with moderate or severe undernutrition (UN group) and 61 healthy children (HC group) to identify associated taxa and genes using a two-stage validation scheme. At stage I, 54 UN patients and 51 healthy children were enrolled for the discovery of GM markers in UN children. The accuracy of the markers was then tested in an additional 11 UN patients and 10 healthy children at stage II. Compared to the HC group, the UN group had lower richness in microbial genes (

Indexed as

Bacteroideschildhood undernutritiongut microbiome markersiron transporternutritional indicators

Identifiers

PMID31849851
PMCPMC6895006
OpenAlexW2989938597

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.