ArticleFrontiers in neurology2019
Assessing Performance on Digital Clock Drawing Test in Aged Patients With Cerebral Small Vessel Disease.
Article in Frontiers in neurology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
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Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Digital Clock Drawing as an Alzheimer's Disease Susceptibility Biomarker: Associations with Genetic Risk Score and APOE in Older Adults.The journal of prevention of Alzheimer's disease · 2024Pooled it
- Higher Amyloid and Tau Burden Is Associated With Faster Decline on a Digital Cognitive Test.Annals of clinical and translational neurology · 2026Article
- Plasma Semaphorin 3A as a Potential Biomarker for Cognitive Impairment in Cerebral Small Vessel Disease.International journal of general medicine · 2025Article
- Performance of the digital trail making test in older adults with white matter lesions.Frontiers in human neuroscience · 2025Article
- Performance of the walking trail making test in older adults with white matter hyperintensities.World journal of psychiatry · 2024Article
- Contributions of Cardiovascular Burden, Peripheral Inflammation, and Brain Integrity on Digital Clock Drawing Performance in Non-Demented Older Adults.Journal of Alzheimer's disease : JAD · 2023Article
- Detecting apathy in patients with cerebral small vessel disease.Frontiers in aging neuroscience · 2022Article
- Executive Performance Is Associated With Rest-Activity Rhythm in Nurses Working Rotating Shifts.Frontiers in neuroscience · 2022Article
- Spatial Navigation Is Impaired in Elderly Patients With Cerebral Small Vessel Disease.Frontiers in neurology · 2021Article
- Digital Technology Differentiates Graphomotor and Information Processing Speed Patterns of Behavior.Journal of Alzheimer's disease : JAD · 2021Article
- Cognitive Frailty Among Elderly Chinese Patients With Cerebral Small Vessel Disease: A Structural MRI Study.Frontiers in medicine · 2020Article
- Validation of SATURN, a free, electronic, self-administered cognitive screening test.Alzheimer's & dementia (New York, N. Y.) · 2020Article
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The term small vessel disease (SVD) encompasses all the pathological processes that affect the small vessels of the brain, including small arteries and arterioles but also capillaries and small veins, which can result in multi-domain cognitive deficits. The digital clock drawing test (dCDT) has been proved to be a more useful assessment tool for cognitive disorders compared to traditional clock drawing test DT (tCDT) in many neuropsychological diseases. This study aimed to check whether this tool worked well in capturing some specific aspects of cognitive performance in aged patients with SVD. A total of 20 aged patients with high-burden SVD (severe-SVD), 10 aged patients with low burden SVD (low-SVD), and 10 age-matched (healthy) individuals were grouped according to Fazekas' score. The dCDT and a series of neuropsychological assessments were performed to evaluate the cognitive function of participants. severe-SVD patients showed higher air-time percentage and lower mean handwriting/drawing pressure on surface during drawing compared with low-SVD and healthy subjects. The linear regression analysis adjusted for age, gender and education showed that the air-time percentage during drawing correlated with the choice reaction test (CRT) and the digit symbol substitution test (DSST), and the mean handwriting/drawing pressure on surface showed a limited correlation with DSST. The data indicated that some early manifestations of cognitive deficits in aged patients with SVD could be detected using the dCDT with a brand-new perspective different from the tCDT.
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