ArticleFrontiers in physiology2019
Exhaled Volatile Organic Compounds Precedes Pulmonary Injury in a Swine Pulmonary Oxygen Toxicity Model.
Article in Frontiers in physiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
6 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.
- Association of Arterial Hyperoxia With Outcomes in Critically Ill Children: A Systematic Review and Meta-analysis.JAMA network open · 2022Pooled it
- The effect of low flow anesthesia with sevoflurane on oxidative status: A prospective, randomized study.Saudi medical journal · 2022Trial
- Effects of hyperbaric air exposure with oxygen breathing during decompression on the exhaled volatile organic compounds.Frontiers in physiology · 2026Article
- Electronic Nose Analysis of Exhaled Breath Volatile Organic Compound Profiles during Normoxia, Hypoxia, and Hyperoxia.Molecules (Basel, Switzerland) · 2024Article
- HS-GC-MS analysis of volatile organic compounds after hyperoxia-induced oxidative stress: a validation study.Intensive care medicine experimental · 2024Article
- Exhaled Nitric Oxide and Pulmonary Oxygen Toxicity Susceptibility.Metabolites · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeInspiring high partial pressure of oxygen (FiO
methodsMale Yorkshire swine (20-30 kg) were placed into custom airtight runs and randomized to air (0.209 FiO
resultsSwine exposed to hyperoxia developed pulmonary injury consistent with PO
conclusionExposing swine to 72 h of hyperoxia induced a pulmonary injury consistent with human clinical endpoints of PO
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.