Evidence map›Paper›PMID 31849661›Full record

ArticleFrontiers in pharmacology2019

Pharmacological Antagonism of T-Type Calcium Channels Constrains Rebound Burst Firing in Two Distinct Subpopulations of GABA Neurons in the Rat Ventral Tegmental Area: Implications for α-Lipoic Acid.

Taylor Joel Woodward, Vesna Tesic, Tamara Timic Stamenic, Vesna Jevtovic-Todorovic, Slobodan M Todorovic

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Taylor Joel WoodwardProgram in Neuroscience, Indiana University-Bloomington, Bloomington, IN, United States.
Vesna TesicDepartment of Anesthesiology, University of Colorado, Aurora, CO, United States.
Tamara Timic StamenicDepartment of Anesthesiology, University of Colorado, Aurora, CO, United States.
Vesna Jevtovic-TodorovicDepartment of Anesthesiology, University of Colorado, Aurora, CO, United States.
Slobodan M TodorovicDepartment of Anesthesiology, University of Colorado, Aurora, CO, United States.
University of Colorado Anschutz Medical Campus · USUniversity of Colorado Denver · US

Funding

In vivo imaging of thalamocortical excitability during anesthesiaR01GM102525 · NIGMS · UNIVERSITY OF VIRGINIA · PI TODOROVIC, SLOBODAN M. · 2014 to 2020
$2.0M
BLRD VA I01 BX004763NIGMS NIH HHS R01 GM102525
6 · The paper itself

Abstract

The ventral tegmental area (VTA) is a midbrain region highly involved in motivation and reward. A large body of work has investigated synaptic plasticity and ion channel excitability in this area, which has strong implication in drug abuse. We recently provided electrophysiological and pharmacological evidence that the Ca

Indexed as

burst firinggamma-amino-butyric acidlipoic acidlow-voltage-activatedrebound spikingT-type calcium channelventral tegmental area

Identifiers

PMID31849661
PMCPMC6889856
OpenAlexW2990651267

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.