Evidence map›Paper›PMID 31849633›Full record

ArticleFrontiers in neuroinformatics2019

QUINT: Workflow for Quantification and Spatial Analysis of Features in Histological Images From Rodent Brain.

Sharon C Yates, Nicolaas E Groeneboom, Christopher Coello, Stefan F Lichtenthaler, Peer-Hendrik Kuhn, Hans-Ulrich Demuth, Maike Hartlage-Rübsamen, Steffen Roßner, Trygve Leergaard, Anna Kreshuk and 2 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in neuroinformatics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 79 papers.

0numbers the graph read from it
0cells of the map it votes in
79citing papers in PubMed
5.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

79 citing papers in PubMed, 137 citations in OpenAlex.

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19 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 6 institutions in 2 countries.

Sharon C YatesNeural Systems Laboratory, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway.
Nicolaas E GroeneboomNeural Systems Laboratory, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway.
Christopher CoelloNeural Systems Laboratory, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway.
Stefan F LichtenthalerGerman Center for Neurodegenerative Diseases (DZNE), Munich, Germany.
Peer-Hendrik KuhnInstitute of Pathology, Technical University of Munich, Munich, Germany.
Hans-Ulrich DemuthDepartment of Molecular Drug Design and Target Validation Fraunhofer Institute for Cell Therapy and Immunology, Halle (Saale), Leipzig, Germany.
Maike Hartlage-RübsamenPaul Flechsig Institute for Brain Research, University of Leipzig, Leipzig, Germany.
Steffen RoßnerPaul Flechsig Institute for Brain Research, University of Leipzig, Leipzig, Germany.
Trygve LeergaardNeural Systems Laboratory, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway.
Anna KreshukEuropean Molecular Biology Laboratory, Heidelberg, Germany.
Maja A PuchadesNeural Systems Laboratory, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway.
Jan G BjaalieNeural Systems Laboratory, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway.
University of Oslo · NOLeipzig University · DEEuropean Molecular Biology Laboratory · DEFraunhofer Institute for Cell Therapy and Immunology · DEMunich Cluster for Systems Neurology · DETechnical University of Munich · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Transgenic animal models are invaluable research tools for elucidating the pathways and mechanisms involved in the development of neurodegenerative diseases. Mechanistic clues can be revealed by applying labelling techniques such as immunohistochemistry or

Indexed as

Alzheimer’s diseaseAPP—amyloid precursor proteinbeta-amyloidquantificationrodent brain analysisworkflow

Identifiers

PMID31849633
PMCPMC6901597
OpenAlexW2991741056

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.