Trial reportClinical interventions in aging2019
Effect of Multicomponent Exercise and Nutrition Support on the Cognitive Function of Older Adults: A Randomized Controlled Trial.
Trial report in Clinical interventions in aging, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 6 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 6 syntheses or guidelines pooled it.
- Effects of exercise interventions on cognitive function in sedentary adults: a systematic review and network meta-analysis.Frontiers in public health · 2026Pooled it
- Multidomain interventions for sarcopenia and cognitive flexibility in older adults for promoting healthy aging: a systematic review and meta-analysis of randomized controlled trials.Aging clinical and experimental research · 2024Pooled it
- Multimodal cognitive and behavioral interventions for patients with MCI: a systematic review and meta-analysis on cognition and mood.Frontiers in aging neuroscience · 2024Pooled it
- Pooled it
- The Therapeutic Impact of Plant-Based and Nutritional Supplements on Anxiety, Depressive Symptoms and Sleep Quality among Adults and Elderly: A Systematic Review of the Literature.International journal of environmental research and public health · 2023Pooled it
- Effect of flavonoids on skeletal muscle mass, strength and physical performance in middle-aged and older adults with or without Sarcopenia: A meta-analysis of randomized controlled trials.Frontiers in nutrition · 2022Pooled it
- The Effects of Exergaming on Executive and Physical Functions in Older Adults With Dementia: Randomized Controlled Trial.Journal of medical Internet research · 2023Trial
- Review
- Effects of an Eight-Week Psychomotor Processing Speed Program on Physical and Cognitive Abilities in Community-Dwelling Older Adults.Perceptual and motor skills · 2026Article
- Dietary Bioactives and Physical Activity in the Regulation of Hippocampal Neurogenesis and Cognitive Decline.Food science & nutrition · 2026Review
- Integrated effects of a 12-week intermittent combined exercise on cognitive function, physical performance, and neurophysiological biomarkers in older women.Journal of exercise rehabilitation · 2025Article
- Move to Remember: The Role of Physical Activity and Exercise in Preserving and Enhancing Cognitive Function in Aging-A Narrative Review.Geriatrics (Basel, Switzerland) · 2025Review
- Impact of Behavioral Changes in Motor Function Measurement on Presenteeism: A Prospective Study.Health science reports · 2025Article
- Effect of IIFAR information nursing model and comprehensive rehabilitation training on negative emotions and rehabilitation outcomes in elderly hemiplegic stroke patients.African health sciences · 2025Article
- Association of depressive symptoms with Geriatric Locomotive Function Scale score in community-dwelling older adults living in the state of emergency.BMC geriatrics · 2023Article
- Factors affecting chronic low back pain among high school baseball players in Japan: A pilot study.PloS one · 2023Article
- Improvement of memory function via a combination of exercise and soy peptide supplementation in community-dwelling older adults: A randomized controlled trial.Contemporary clinical trials communications · 2022Article
- Interdisciplinary Approaches to Deal with Alzheimer's Disease-From Bench to Bedside: What Feasible Options Do Already Exist Today?Biomedicines · 2022Review
- Nicotinic acid supplementation contributes to the amelioration of Alzheimer's disease in mouse models.Annals of translational medicine · 2022Article
- Modifiable Innate Biology within the Gut-Brain Axis for Alzheimer's Disease.Biomedicines · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThis study compared the effects of a combination of soy peptide supplementation and exercise with those of exercise only, on the cognitive function of elderly adults. PATIENTS AND
methodsThis randomized, non-blinded, controlled clinical trial included 67 participants aged 60 years or more with non-cognitive dysfunction who were divided into two groups according to the intervention method: an exercise group (Ex group, n = 36) and an exercise plus nutrition group (Ex+Nt group, n = 31). The Ex group completed a memory training activity for 15 mins and aerobic exercise for 45 mins once a week for 90 days. The Ex+Nt group completed the same training plus received soy peptide for 90 days. The Mini-Mental Status Examination score, trail-making test A/B score, skeletal muscle mass index, grip strength, gait speed, and geriatric depression scale were measured at baseline and post intervention. For comparison between the pretest and posttest measurements to determine the intervention effects, a two-way analysis of variance was performed. The significance level was set at < 5%.
resultsA two-way analysis of variance revealed significant time effects on trail-making test-A score, skeletal muscle index, grip strength, and gait speed in both groups. There were significant time x group interactions for greater increase in calculation score.
conclusionA combination of exercise and soy peptide supplementation was effective in improving a portion of cognitive function.
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Registered trials
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