ArticleBMC microbiology2019
Genetic diversity of Listeria monocytogenes strains in ruminant abortion and rhombencephalitis cases in comparison with the natural environment.
Article in BMC microbiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 1 of them a synthesis that pooled it.
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Who cites it
33 citing papers in PubMed, 1 synthesis or guideline pooled it, 51 citations in OpenAlex.
- Epidemiology, clinical and pathological features and outcomes of listeriosis in ruminants: a systematic review and meta-analysis.The veterinary quarterly · 2025Pooled it
- An outbreak of septicemic listeriosis associated with diarrhea in lactating dairy cows.The Journal of veterinary medical science · 2026Article
- Genomic characterization of Listeria monocytogenes isolated from small ruminants in integrated crop-livestock systems.BMC microbiology · 2026Article
- Article
- Investigation ofArchives of Razi Institute · 2025Article
- Prevalent Infectious Causes of Abortion in the Ruminant Population in Iran- A Literature Review.Archives of Razi Institute · 2025Review
- The inactivated and ISA 61 VG adjuvanted vaccine enhances protection against cross-serotype Listeria monocytogenes.Veterinary research · 2025Article
- Listeriosis: Characteristics, Occurrence in Domestic Animals, Public Health Significance, Surveillance and Control.Microorganisms · 2024Review
- High density genomic surveillance and risk profiling of clinical Listeria monocytogenes subtypes in Germany.Genome medicine · 2024Article
- Genomic characterization ofFrontiers in microbiology · 2024Article
- Genomic epidemiology of the clinically dominant clonal complex 1 in theMicrobial genomics · 2024Article
- Identification by High-Throughput Real-Time PCR of 30 Major Circulating Listeria monocytogenes Clonal Complexes in Europe.Microbiology spectrum · 2023Article
- Natural Isoforms ofInternational journal of molecular sciences · 2023Article
- In Vitro and In Vivo Virulence Study ofTropical medicine and infectious disease · 2023Article
- Transmission Scenarios ofFoods (Basel, Switzerland) · 2023Review
- Comparative Genomics of Listeria monocytogenes Isolates from Ruminant Listeriosis Cases in the Midwest United States.Microbiology spectrum · 2022Article
- Genome-Wide Association Study ofMicroorganisms · 2022Article
- Co-Infection ofMicroorganisms · 2022Article
- A European-wide dataset to uncover adaptive traits of Listeria monocytogenes to diverse ecological niches.Scientific data · 2022Article
- Whole-Genome Sequencing Analysis of Listeria monocytogenes from Rural, Urban, and Farm Environments in Norway: Genetic Diversity, Persistence, and Relation to Clinical and Food Isolates.Applied and environmental microbiology · 2022Article
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Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundListeria monocytogenes is the causative agent of listeriosis, a serious disease affecting both animals and humans. Here, multilocus sequence typing (MLST) was used to characterize the genetic diversity of Listeria monocytogenes strains isolated from the natural environment and animal clinical cases in Europe. The prevalence of clonal complexes (CCs) obtained was compared according to (i) the origin of isolation - clinical cases vs. natural environment - and (ii) the clinical form of animal listeriosis - rhombencephalitis vs. abortion. To this aim, two datasets were constructed. The clinical dataset consisted of 350 animal clinical isolates originating from France and Slovenia and supplemented with isolates from Switzerland and Great Britain. The natural environment dataset consisted of 253 isolates from the natural environment originating from Slovenia and supplemented with isolates from nine other European countries.
resultsFor the clinical cases, CC1, CC4-CC217 and CC412 were the most prevalent in rhombencephalitis and CC1, CC37 and CC4-CC217 in abortion. The hypervirulent CC1 and CC4-CC217 prevailed in both datasets. These results indicated that livestock is constantly exposed to hypervirulent CCs. CC1 was significantly associated with a clinical origin, whereas CC9, CC29 and CC14 were associated with the natural environment. CC1 was predominant among rhombencephalitis cases both in cattle and small ruminants, and its prevalence did not differ significantly between these two groups. A novel association of CC37 and CC6 with abortion cases was revealed.
conclusionsHere, we show that CC1 and CC4-CC217 are prevalent in isolates of environmental and animal clinical origin, suggesting that ruminants are frequently exposed to hypervirulent CCs. The presence of CC4 in two mastitis cases calls for further attention due to direct threat to the consumer. We showed several associations between CCs and the origin of isolation or clinical form of listeriosis, e.g. CC37 and CC6 with abortion. This study improves our understanding of the population structure of L. monocytogenes isolates from the natural environment and animal clinical cases. Moreover, it provides a basis for future studies aiming to determine the underlying mechanisms of phenotypic traits of interest.
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