Evidence map›Paper›PMID 31849201›Full record

ArticleMaternal & child nutrition2020

Egg intervention effect on linear growth no longer present after two years.

Lora L Iannotti, Melissa Chapnick, Jennifer Nicholas, Carlos Andres Gallegos-Riofrio, Patricia Moreno, Katherine Douglas, David Habif, Yuhan Cui, Christine Stewart, Chessa K Lutter and 1 more

Open access · hybridAbstract read
In one paragraph

Article in Maternal & child nutrition, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.

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  18. Frontiers in public health · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 2 countries.

Lora L IannottiInstitute for Public Health, Brown School, Washington University in St. Louis, St. Louis, Missouri.ORCID 0000-0001-8826-0867
Melissa ChapnickInstitute for Public Health, Brown School, Washington University in St. Louis, St. Louis, Missouri.
Jennifer NicholasSchool of Medicine, Pediatric Radiology, Mallinckrodt Institute of Radiology, Washington University in St. Louis, St. Louis, Missouri.
Carlos Andres Gallegos-RiofrioInstitute for Public Health, Brown School, Washington University in St. Louis, St. Louis, Missouri.
Patricia MorenoInstituto de Investigación en Salud y Nutrición, Diego de Robles y Via Interoceánica, Universidad San Francisco de Quito, Quito, Ecuador.
Katherine DouglasSchool of Medicine, Pediatric Radiology, Mallinckrodt Institute of Radiology, Washington University in St. Louis, St. Louis, Missouri.
David HabifInstitute for Public Health, Brown School, Washington University in St. Louis, St. Louis, Missouri.
Yuhan CuiInstitute for Public Health, Brown School, Washington University in St. Louis, St. Louis, Missouri.
Christine StewartDepartment of Nutrition, University of California Davis, Davis, California.ORCID 0000-0003-4575-8571
Chessa K LutterPAHO, Food Security and Agriculture, RTI International, Washington, DC, United States.ORCID 0000-0003-1601-4645
William F WatersInstituto de Investigación en Salud y Nutrición, Diego de Robles y Via Interoceánica, Universidad San Francisco de Quito, Quito, Ecuador.ORCID 0000-0001-6222-8551
Washington University in St. Louis · USUniversidad San Francisco de Quito · ECInternational Food Policy Research Institute · USUniversity of California, Davis · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Lulun Project, a randomized controlled trial conducted in 2015, found that one egg per day for 6 months during early complementary feeding reduced stunting by 47% and increased linear growth by 0.63 length-for-age Z (LAZ). This follow-up cohort study (Lulun Project II) aimed to test whether the growth effect remained in the egg intervention group compared with the control group after approximately 2 years. Mothers or caregivers from the Lulun Project were recontacted and recruited for this study. Enumerators collected data on socio-economic and demographic factors, 24-hr frequency of dietary intakes, morbidities, and anthropometric measures of height, weight, and head circumference using World Health Organization protocols. Statistical analyses followed the same analytical plan as Lulun Project, applying generalized linear models and regression modelling to test group differences in height-for-age z (HAZ) from LAZ at Lulun Project endline, and structural equation modelling for mediation. One hundred thirty-five mother-child dyads were included in Lulun II, with 11% losses to follow-up from endline Lulun Project. Growth faltering across all children was evident with HAZ -2.07 ± 0.91 and a stunting prevelance of 50%. Regression modelling showed no difference between egg and control groups for the HAZ outcome and other anthropometric outcomes, and significant declines in HAZ from endline Lulun Project in the egg intervention are compared with control groups. Current dietary egg intake, however, was associated with reduced growth faltering in HAZ from Lulun Project endline to Lulun Project II, independent of group assignment and through mediation, explaining 8.8% of the total effect. Findings suggest the need for a longer intervention period and ongoing nutrition support to young children during early childhood.

Indexed as

Body HeightChild DevelopmentEggsAnthropometryBody WeightChild, PreschoolDietEcuadorFemaleFollow-Up StudiesGrowth DisordersHumansLongitudinal StudiesMaleanimal source foodscohort studycomplementary feedingcomplementary foodsEcuadoregg nutritioninfant growthpreschool childrenstunting

Identifiers

PMID31849201
PMCPMC7083396
OpenAlexW2996240824

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.