Evidence map›Paper›PMID 31849117›Full record

ArticleChemistry (Weinheim an der Bergstrasse, Germany)2020

Halogen Bonding Interactions of Polychlorinated Biphenyls and the Potential for Thyroid Disruption.

Eric S Marsan, Craig A Bayse

Open access · greenAbstract read
In one paragraph

Article in Chemistry (Weinheim an der Bergstrasse, Germany), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 20 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Eric S MarsanDepartment of Chemistry and Biochemistry, Old Dominion University, 1 Old Dominion University, Norfolk, VA, 23529, USA.ORCID http://orcid.org/0000-0003-3862-7485
Craig A BayseDepartment of Chemistry and Biochemistry, Old Dominion University, 1 Old Dominion University, Norfolk, VA, 23529, USA.ORCID http://orcid.org/0000-0002-3490-576X
Old Dominion University · US

Funding

Molecular modeling of the activity and inhibition of the thryoid enzyme iodothyronine deiodinaseR15GM119063 · NIGMS · OLD DOMINION UNIVERSITY · PI BAYSE, CRAIG A · 2017 to 2017
$433k
NIGMS NIH HHS R15 GM119063NIH HHS R15 GM119063-01A1
6 · The paper itself

Abstract

Polychlorinated biphenyl (PCB) flame retardants are persistent pollutants and inhibit neurodevelopment, particularly in the early stages of life. Halogen bonding (XB) to the iodothyronine deiodinases (Dio) that modulate thyroid hormones (THs) is a potential mechanism for endocrine disruption. Cl⋅⋅⋅Se XB interactions of PCBs with SeMe

Indexed as

Environmental PollutantsHalogensHumansIodide PeroxidasePolychlorinated BiphenylsThyroid GlandThyroid HormonesEnvironmental PollutantsHalogensIodide PeroxidasePolychlorinated BiphenylsThyroid Hormonesdensity functional theoryhalogen bondingiodothyronine deiodinasepolychlorinated biophenylsthyroid hormones

Identifiers

PMID31849117
PMCPMC8812442
OpenAlexW2995444485

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.