Evidence map›Paper›PMID 31849001›Full record

ArticleEating and weight disorders : EWD2020

Venous thromboembolism in anorexia nervosa: four cases from a specialized unit. Indication for thromboprophylaxis?

Zainab Abdelhadi, Else Marie Bladbjerg, Dorte Møller Jensen, Amalie Schousboe, René Klinkby Støving

Abstract readCase Reports
PubMed Publisher
In one paragraph

Article in Eating and weight disorders : EWD, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Observational
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Zainab AbdelhadiCenter for Eating Disorders, Odense University Hospital, Odense, Denmark.ORCID http://orcid.org/0000-0003-0187-7173
Else Marie BladbjergUnit for Thrombosis Research, Department of Regional Health Research, The University of Southern Denmark, Odense, Denmark.ORCID http://orcid.org/0000-0003-0912-2437
Dorte Møller JensenSteno Diabetes Center Odense, Odense University Hospital, Odense, Denmark.ORCID http://orcid.org/0000-0002-3298-9824
Amalie SchousboeElite Research Center for Medical Endocrinology, Odense University Hospital, Odense, Denmark.ORCID http://orcid.org/0000-0003-1081-3884
René Klinkby StøvingCenter for Eating Disorders, Odense University Hospital, Odense, Denmark. rene.stoeving@rsyd.dk.ORCID http://orcid.org/0000-0002-4255-5544
Odense University Hospital · DKUniversity of Southern Denmark · DKSteno Diabetes Centers · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundVenous thromboembolism (VTE), which includes deep vein thrombosis (DVT) and pulmonary embolism (PE), is a major cause of mortality and morbidity. VTE may occur asymptomatic or subclinical. Fluid retention during intensive re-nutrition or rapid weight changes are well-known phenomena in anorexia nervosa (AN) and may represent a significant risk factor for VTE.

objectiveThe incidence of VTE in patients with AN is unknown, and the conditions may be overlooked in a complex clinical picture.

methodThis study report four cases of VTE in women with severe AN (age range 19-41 years, BMI range 10.6-13.1) admitted to a specialized unit for medical stabilization.

resultsDVT or PE was diagnosed in all four patients. The patients were admitted for intensive re-nutrition according to conventional conservative guidelines with slow increase in energy supply (start low and advance slow). Due to suspected VTE, thromboprophylaxis was given during hospitalization, three of whom were undergoing re-nutrition.

conclusionThe four presented cases suggest that VTE during re-nutrition in AN may be an overlooked risk which may not be sufficiently addressed in the literature. General recommendations should not be issued on the basis of case reports; however, we want to raise awareness and call for studies to identify the VTE risk and appropriate thromboprophylaxis in AN patients.

Indexed as

Anorexia NervosaPulmonary EmbolismVenous ThromboembolismAdultAnticoagulantsFemaleHumansRisk FactorsYoung AdultAnticoagulantsAnorexia nervosaDeep vein thrombosisPulmonary embolismRefeeding syndromeVenous thromboembolism

Identifiers

PMID31849001
OpenAlexW2995641945

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.