Evidence map›Paper›PMID 31848927›Full record

ArticleJournal of clinical psychology in medical settings2021

Fear of Cancer Recurrence and Death Anxiety: Unaddressed Concerns for Adult Neuro-oncology Patients.

Ashlee R Loughan, Autumn Lanoye, Farah J Aslanzadeh, Audrey Ann Lois Villanueva, Rachel Boutte, Mariya Husain, Sarah Braun

Abstract read
In one paragraph

Article in Journal of clinical psychology in medical settings, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. How young cancer patients cope with death anxiety: a qualitative study based on terror management theory.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Article
  4. Review
  5. Article
  6. Article
  7. Neuro-oncology practice · 2025
    Article
  8. Neuro-oncology practice · 2025
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. "Not me!" a qualitative, vignette-based study of nurses' and physicians' reactions to spiritual distress on neuro-oncological units.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Palliative Care in Neuro-oncology: an Update.Current neurology and neuroscience reports · 2023
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ashlee R LoughanDepartment of Neurology, Division of Neuro-Oncology, School of Medicine, Virginia Commonwealth University, Richmond, VA, USA. ashlee.loughan@vcuhealth.org.ORCID 0000-0003-1231-2469
Autumn LanoyeDepartment of Health Behavior and Policy, School of Medicine, Virginia Commonwealth University, Richmond, VA, USA.
Farah J AslanzadehDepartment of Psychology, Virginia Commonwealth University, Richmond, VA, USA.
Audrey Ann Lois VillanuevaDepartment of Neurology, Division of Neuro-Oncology, School of Medicine, Virginia Commonwealth University, Richmond, VA, USA.
Rachel BoutteDepartment of Psychology, Virginia Commonwealth University, Richmond, VA, USA.
Mariya HusainDepartment of Neurology, Division of Neuro-Oncology, School of Medicine, Virginia Commonwealth University, Richmond, VA, USA.
Sarah BraunDepartment of Neurology, Division of Neuro-Oncology, School of Medicine, Virginia Commonwealth University, Richmond, VA, USA.

Funding

Research Supplement to Promote Diversity in Health Related ResearchUL1TR002649 · NCATS · VIRGINIA COMMONWEALTH UNIVERSITY · PI MOELLER, FREDERICK GERARD · 2018 to 2022
$19.1M
Institutional Career Development CoreKL2TR002648 · NCATS · VIRGINIA COMMONWEALTH UNIVERSITY · PI NANASINKAM, SERGE PATRICK, SANYAL, ARUN J · 2018 to 2022
$3.7M
CTSA K12 Program at Virginia Commonwealth UniversityK12TR004364 · NCATS · VIRGINIA COMMONWEALTH UNIVERSITY · PI SERGE PATRICK NANASINKAM, Gretchen N Neigh · 2023 to 2026
$3.0M
NCATS NIH HHS K12 TR004364NCATS NIH HHS KL2 TR002648NCATS NIH HHS UL1 TR002649
6 · The paper itself

Abstract

Primary brain tumor (PBT) patients may experience existential distress; however, few studies have examined this issue. The objectives of this study were to (1) systematically review PBT representation in psycho-oncology literature regarding fear/anxiety related to progression, recurrence, and death and (2) preliminarily assess the prevalence of fear of dying in a sample of PBT patients. Systematic searching of three databases yielded 1555 articles for review. Of these, 327 studies met inclusion criteria (patient sample N = 132,951). Only eight studies (0.18% of the participants) included patients with a PBT diagnosis, potentially due to exclusion criteria such as cognitive impairment or specific treatment parameters which may prohibit PBT patient participation. Review of the results from the eight included studies revealed mixed methods and limited demographic analyses; existential distress was correlated with heightened depression and anxiety, and overall worsened quality of life. From the original data collection, approximately one-third of PBT patients endorsed fear of dying, which was positively related to depression severity. Taken together, results suggest that PBT patients are considerably underrepresented in existential psycho-oncology literature, despite preliminary findings suggesting prevalence of these concerns. Future research on existential distress in neuro-oncology is warranted.

Indexed as

Brain NeoplasmsQuality of LifeAdultAnxietyFearHumansPsycho-OncologySystematic Reviews as TopicDeath anxietyExistential distressFear of cancer recurrenceNeuro-oncologyPrimary brain tumor

Identifiers

PMID31848927
PMCPMC7461618

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.