Evidence map›Paper›PMID 31848467›Full record

ReviewNature reviews. Cancer2020

Dietary patterns and cancer risk.

Susan E Steck, E Angela Murphy

Registry-linked trialAbstract readReview
PubMed Publisher
In one paragraph

Review in Nature reviews. Cancer, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05678426 (TirolGESUND), which is not on this map. Cited by 175 papers, 12 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
175citing papers in PubMed, 12 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05678426 nacompletednot on this mapstarted 2021, after this paper: background citation

TirolGESUND: General Exercise, Smoking Undone, and Nutrition Diet

TypeinterventionalSponsorUniversitaet InnsbruckRan2021 to 2025Enrolled156ConditionsHealthy, Healthy Lifestyle, Smoking Cessation, Intermittent FastingArmsSmoking cessation, Intermittent fasting, Intermittent fasting with ketogenic supplement
3 · Its place in the literature

Who cites it

175 citing papers in PubMed, 12 syntheses or guidelines pooled it.

  1. Dietary Pattern and Risk of Thyroid Cancer: A Systematic Review.Journal of human nutrition and dietetics : the official journal of the British Dietetic Association · 2026
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115 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Susan E SteckDepartment of Epidemiology & Biostatistics, Arnold School of Public Health, University of South Carolina, Columbia, SC, USA. stecks@mailbox.sc.edu.ORCID http://orcid.org/0000-0002-3201-9537
E Angela MurphyDepartment of Pathology, Microbiology and Immunology, School of Medicine, University of South Carolina, Columbia, SC, USA.

Funding

Emodin as a chemopreventive agent for breast cancer - admin suppR01CA218578 · NCI · UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA · PI FAN, DAPING, MURPHY, ELIZABETH ANGELA · 2018 to 2022
$1.9M
NCI NIH HHS R01 CA218578
6 · The paper itself

Abstract

Over the past decade, the search for dietary factors on which to base cancer prevention guidelines has led to the rapid expansion of the field of dietary patterns and cancer. Multiple systematic reviews and meta-analyses have reported epidemiological associations between specific cancer types and both data-driven dietary patterns determined by empirical analyses and investigator-defined dietary indexes based on a predetermined set of dietary components. New developments, such as the use of metabolomics to identify objective biomarkers of dietary patterns and novel statistical techniques, could provide further insights into the links between diet and cancer risk. Although animal models of dietary patterns are limited, progress in this area could identify the potential mechanisms underlying the disease-specific associations observed in epidemiological studies. In this Review, we summarize the current state of the field, provide a critical appraisal of new developments and identify priority areas for future research. An underlying theme that emerges is that the effectiveness of different dietary pattern recommendations in reducing risk could depend on the type of cancer or on other risk factors such as family history, sex, age and other lifestyle factors or comorbidities as well as on metabolomic signatures or gut microbiota profiles.

Indexed as

DietDisease SusceptibilityFeeding BehaviorAnimalsBiomarkersDisease Models, AnimalEnergy MetabolismHumansNeoplasmsRisk AssessmentRisk FactorsBiomarkers

Identifiers

PMID31848467

What OpenQuestion holds

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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.