Evidence map›Paper›PMID 31848397›Full record

ArticleScientific reports2019

Determining the Hierarchical Architecture of the Human Brain Using Subject-Level Clustering of Functional Networks.

Teddy J Akiki, Chadi G Abdallah

Abstract read
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers.

0numbers the graph read from it
0cells of the map it votes in
50citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

50 citing papers in PubMed.

  1. Trial
  2. A robust and reproducible connectome fingerprint of ketamine is highly associated with the connectomic signature of antidepressants.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2021
    Trial
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Neural circuit basis of pathological anxiety.Nature reviews. Neuroscience · 2025
    Review
  11. Article
  12. Article
  13. Flexible Bayesian Product Mixture Models for Vector Autoregressions.Journal of machine learning research : JMLR · 2024
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Teddy J AkikiClinical Neurosciences Division-National Center for PTSD, United States Department of Veterans Affairs, West Haven, CT, 06516, USA.ORCID http://orcid.org/0000-0003-1988-9201
Chadi G AbdallahClinical Neurosciences Division-National Center for PTSD, United States Department of Veterans Affairs, West Haven, CT, 06516, USA. chadi.abdallah@yale.edu.ORCID http://orcid.org/0000-0001-5783-6181

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
NCATS NIH HHS UL1 TR001863U.S. Department of Health & Human Services | National Institutes of Health (NIH) MH-101498
6 · The paper itself

Abstract

Optimal integration and segregation of neuronal connections are necessary for efficient large-scale network communication between distributed cortical regions while allowing for modular specialization. This dynamic in the cortex is enabled at the network mesoscale by the organization of nodes into communities. Previous in vivo efforts to map the mesoscale architecture in humans had several limitations. Here we characterize a consensus multiscale community organization of the functional cortical network. We derive this consensus from the clustering of subject-level networks. We applied this analysis to magnetic resonance imaging data from 1003 healthy individuals part of the Human Connectome Project. The hierarchical atlas and code will be made publicly available for future investigators.

Indexed as

ConnectomeAdultBrainCluster AnalysisFemaleHumansImage Processing, Computer-AssistedMagnetic Resonance ImagingMaleNerve NetNeural PathwaysNeurons

Identifiers

PMID31848397
PMCPMC6917755

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.